N-(9-Hydroxy-9H-fluoren-2-yl)acetamide

Base Information

Chemical Name:N-(9-Hydroxy-9H-fluoren-2-yl)acetamide
CAS No.:57229-41-1
Molecular Formula:C15H13NO2
Molecular Weight:239.29
Hs Code.:
NSC Number:12397
DSSTox Substance ID:DTXSID501283157
Nikkaji Number:J74.894C
ChEMBL ID:CHEMBL303825

Synonyms:N-(9-Hydroxy-9H-fluoren-2-yl)acetamide;57229-41-1;2-Acetylamino-9-fluorenol;9-Hydroxy-2-fluorenylacetamide;9-Hydroxyacetylaminofluorene;N-(9-Hydroxyfluoren-2-yl)acetamide;ACETAMIDE, N-(9-HYDROXYFLUOREN-2-YL)-;CCRIS 7422;BRN 2738196;N-(9-Hydroxy-9H-fluoren-2-yl)-acetamide;CHEMBL303825;Acetamide, N-(9-hydroxy-9H-fluoren-2-yl)-;4-13-00-02241 (Beilstein Handbook Reference);NSC12397;starbld0007229;9-hydroxy-2-acetylaminofluorene;SCHEMBL22321745;DTXSID501283157;BDBM50038929;NSC 12397;NSC-12397;WLN: L B656 HHJ EMV1 HQ;LS-9700;N-(9-Hydroxy-9H-fluoren-2-yl)acetamide #

Suppliers and Price of N-(9-Hydroxy-9H-fluoren-2-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(9-Hydroxy-9H-fluoren-2-yl)-acetamide
50mg
$ 2310.00

American Custom Chemicals Corporation
N-(9-HYDROXY-9H-FLUOREN-2-YL)ACETAMIDE 95.00%
5MG
$ 505.90

Total 4 raw suppliers

Chemical Property of N-(9-Hydroxy-9H-fluoren-2-yl)acetamide

Chemical Property:

Vapor Pressure:8.72E-12mmHg at 25°C
Refractive Index:1.5500 (estimate)
Boiling Point:523.5°Cat760mmHg
Flash Point:270.4°C
PSA：49.33000
Density:1.341g/cm³
LogP:2.78010
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:239.094628657
Heavy Atom Count:18
Complexity:331

Purity/Quality:

99% ^*data from raw suppliers

N-(9-Hydroxy-9H-fluoren-2-yl)-acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C2O
Uses N-(9-Hydroxy-9H-fluoren-2-yl)-acetamide is a liver produced metabolite of the cancinogens 2-acetamidofluorene (A158535), which can be activated by liver homogenate and formed potent frameshift mutagens. It is used to study the mechanism of liver carcinogenesis and as a reference material during its identification or quantitation.

Technology Process of N-(9-Hydroxy-9H-fluoren-2-yl)acetamide

There total 4 articles about N-(9-Hydroxy-9H-fluoren-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 3096-50-2
2-acetylamino-9-fluorenone

: 57229-41-1
9-Hydroxy-2-acetylaminofluorene

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

Reference yield:

: 3096-57-9
2-amino-9-fluorenone

: 57229-41-1
9-Hydroxy-2-acetylaminofluorene

Guidance literature:: Multi-step reaction with 2 steps

1: methanol; NaBH₄

2: acetic acid

With methanol; sodium tetrahydroborate; acetic acid;
DOI:10.1021/jo01100a008