Retinyl methyl ether

Base Information

• Chemical Name: Retinyl methyl ether
• CAS No.: 32450-56-9
• Molecular Formula: C21H32 O
• Molecular Weight: 300.484
• European Community (EC) Number: 251-054-9
• DSSTox Substance ID: DTXSID001315393
• Nikkaji Number: J82.347C
• Mol file: 32450-56-9.mol

Synonyms:retinyl methyl ether

Chemical Property of Retinyl methyl ether

Chemical Property:

• Vapor Pressure: 1.7E-06mmHg at 25°C
• Melting Point: 55 °C(Solv: methanol (67-56-1); acetone (67-64-1))
• Boiling Point: 408.1°Cat760mmHg
• Flash Point: 188.3°C
• PSA: 9.23000
• Density: 0.923g/cm³
• LogP: 6.16440
• XLogP3: 6.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 300.245315640
• Heavy Atom Count: 22
• Complexity: 510

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC)C)C
• Isomeric SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/COC)/C)/C

Technology Process of Retinyl methyl ether

There total 27 articles about Retinyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

9-(2,6,6-Trimethyl-cyclohex-1-enyl)-5-phenyl-sulphonyl-3,7-dimethyl-1-methoxy-nona-2,6,8-triene (50465-62-8) → retinyl methyl ether (32450-56-9)

Guidance literature:

With sodium ethanolate; In ethanol; Heating;

Reference yield: 54.0%

(2E,5E,7E)-9-Methoxy-3,7-dimethyl-1-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,5,7-trien-4-ol (188965-81-3) → retinyl methyl ether (32450-56-9)

Guidance literature:

With pyridine; trichlorophosphate; In toluene; at 50 ℃;

DOI:10.1016/S0040-4039(97)00459-0

Reference yield:

RETINOL (68-26-8) → retinyl methyl ether (32450-56-9)

Guidance literature:

With n-butyllithium; Petroleum ether; benzene; anschliessendes Behandeln mit Dimethylsulfat in Benzol bei 70grad in gedaempftem Licht;

DOI:10.1021/ja01211a510

upstream raw materials:

(6-bromo-3-methyl-hex-2-en-4-ynyl)-methyl ether

(E)-β-ionone

(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal

(+/-)-9-methoxy-3.7-dimethyl-1-(2.2.6-trimethyl-cyclohexen-(6)-yl)-nonatrien-(2ξ.5c.7c)-ol-(4)

Refernces

• 1、 Lee, Jun Sup,Jeong, Young Cheol,Ji, Minkoo,Baik, Woonphil,Lee, Sijoon,Koo, Sangho. "Highly Efficient and General Synthetic Method of Various Retinyl Ethers". . p. 1937 - 1940. Retrieved 2007/10/03.
• 2、 Rao, V. Jayathirtha,Bhalerao, U. T.. "REGIOSELECTIVE PHOTOISOMERISATION OF RETINOLACETATE". . p. 3441 - 3444. Retrieved 2007/10/02.