3-endo-(8-(2-[(4,4-difluoro-cyclohexylmethyl)-((S)-2,3-dihydroxy-1-oxo-propyl)-amino]-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl)-2-hydroxy-benzamide trifluoroacetate

Base Information

Chemical Name:3-endo-(8-(2-[(4,4-difluoro-cyclohexylmethyl)-((S)-2,3-dihydroxy-1-oxo-propyl)-amino]-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl)-2-hydroxy-benzamide trifluoroacetate
CAS No.:1123662-03-2
Molecular Formula:C₂HF₃O₂*C₂₆H₃₇F₂N₃O₅
Molecular Weight:623.618
Hs Code.:

3-endo-(8-(2-[(4,4-difluoro-cyclohexylmethyl)-((S)-2,3-dihydroxy-1-oxo-propyl)-amino]-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl)-2-hydroxy-benzamide trifluoroacetate

Synonyms:3-endo-(8-(2-[(4,4-difluoro-cyclohexylmethyl)-((S)-2,3-dihydroxy-1-oxo-propyl)-amino]-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl)-2-hydroxy-benzamide trifluoroacetate

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Chemical Property of 3-endo-(8-(2-[(4,4-difluoro-cyclohexylmethyl)-((S)-2,3-dihydroxy-1-oxo-propyl)-amino]-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl)-2-hydroxy-benzamide trifluoroacetate

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Technology Process of 3-endo-(8-(2-[(4,4-difluoro-cyclohexylmethyl)-((S)-2,3-dihydroxy-1-oxo-propyl)-amino]-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl)-2-hydroxy-benzamide trifluoroacetate

There total 1 articles about 3-endo-(8-(2-[(4,4-difluoro-cyclohexylmethyl)-((S)-2,3-dihydroxy-1-oxo-propyl)-amino]-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl)-2-hydroxy-benzamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133481-13-7
lithium (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate

: 1123661-33-5
3-endo-(8-(2-[(4,4-difluorocyclohexylmethyl)amino]-ethyl)-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide

: 76-05-1
trifluoroacetic acid

: 1123662-03-2
3-endo-(8-(2-[(4,4-difluoro-cyclohexylmethyl)-((S)-2,3-dihydroxy-1-oxo-propyl)-amino]-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl)-2-hydroxy-benzamide trifluoroacetate

Guidance literature:: lithium (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate; 3-endo-(8-(2-[(4,4-difluorocyclohexylmethyl)amino]-ethyl)-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide; With HATU; In N,N-dimethyl-formamide;

With water; acetic acid; at 70 ℃;

trifluoroacetic acid;