8-Amino-8-demethylriboflavin

Base Information

Chemical Name:8-Amino-8-demethylriboflavin
CAS No.:5178-05-2
Molecular Formula:C₁₆H₁₉N₅O₆
Molecular Weight:377.357
Hs Code.:
DSSTox Substance ID:DTXSID00966096
Nikkaji Number:J536.063C,J2.773.210K
Wikidata:Q76084672
Mol file:5178-05-2.mol

Synonyms:8-amino-8-demethyl-D-riboflavin;8-amino-8-demethylriboflavin;8-amino-8-demethylriboflavin tetraacetate;8-demethyl-8-aminoriboflavin

Suppliers and Price of 8-Amino-8-demethylriboflavin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 14 raw suppliers

Chemical Property of 8-Amino-8-demethylriboflavin

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.8g/cm³
XLogP3:-2.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:377.13353334
Heavy Atom Count:27
Complexity:682

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC2=C(C=C1N)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(CO)O)O)O
Isomeric SMILES:CC1=CC2=C(C=C1N)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](CO)O)O)O

Technology Process of 8-Amino-8-demethylriboflavin

There total 9 articles about 8-Amino-8-demethylriboflavin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87-39-8
violuric acid

: 5-((3-amino-4-methylphenyl)amino)pentane-1,2,3,4-tetraol

: 56221-68-2,5178-05-2
8-demethyl-8-amino-D-riboflavin

Guidance literature:: In methanol; water; for 4h; Yield given; Heating;
DOI:10.1246/bcsj.60.3041

Reference yield:

: 3-nitro-4-methyl-N-ribitylaniline hydrochloride

: 56221-68-2,5178-05-2
8-demethyl-8-amino-D-riboflavin

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH, H₂ / Raney's catalyst / methanol / 0.5 h / 50 °C

2: methanol; H₂O / 4 h / Heating

With sodium hydroxide; hydrogen; Raney's catalyst; In methanol; water;
DOI:10.1246/bcsj.60.3041

Reference yield:

: 119-32-4
4-Methyl-3-nitroanilin

: 56221-68-2,5178-05-2
8-demethyl-8-amino-D-riboflavin

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium cyanoborohydride / methanol / 48 h / 80 °C / Reflux; Inert atmosphere

2.1: palladium 10% on activated carbon; hydrogen / methanol / 40 °C / 750.08 Torr

3.1: boric acid / water / 12 h / 105 °C

3.2: 6 h / 20 °C

4.1: ammonia / methanol

With palladium 10% on activated carbon; ammonia; hydrogen; boric acid; sodium cyanoborohydride; In methanol; water;
DOI:10.1021/jacs.6b02469