VIOLURIC ACID

Base Information

• Chemical Name: VIOLURIC ACID
• CAS No.: 87-39-8
• Molecular Formula: C4H3 N3 O4
• Molecular Weight: 157.086
• Hs Code.: 2933.52
• Mol file: 87-39-8.mol

Synonyms:Alloxan,5-oxime (8CI); Violuric acid (6CI,7CI); 5-(Hydroxyimino)barbituric acid;5-Isonitrosobarbituric acid; NSC 56338; VLA

Chemical Property of VIOLURIC ACID

Chemical Property:

• Appearance/Colour: white to pale yellow crystalline powder
• Vapor Pressure: 7.79E-12mmHg at 25°C
• Melting Point: 240 - 250 C
• Refractive Index: 1.5000 (estimate)
• Boiling Point: 494.1 ºCat 760 mmHg
• PKA: 4.7(at 25℃)
• Flash Point: 252.6 ºC
• PSA: 107.86000
• Density: 2.19 g/cm³
• LogP: -1.15980
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: Aqueous Acid (Sparingly), DMSO (Sparingly), Methanol (Slightly)
• Water Solubility.: 7.04g/L at 20℃

Purity/Quality:

99.9% ^*data from raw suppliers

VioluricAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): UN NO.
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Analytical reagent for chromatographic separation of cations. Forms chelates: Leermakers, Hoffman, J. Am. Chem. Soc. 80, 5663 (1958). Violuric Acid, can be used for the synthesis of some novel pyrimidines fused aza-heterocycles, having broad spectrum of pharmacological activities, such as 2-Methyloxazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione (M324600).

Technology Process of VIOLURIC ACID

There total 15 articles about VIOLURIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.2%

BARBITURIC ACID (67-52-7,944357-77-1) → violuric acid (87-39-8)

Guidance literature:

With hydrogenchloride; sodium hydroxide; sodium nitrite; In water; at 10 - 30 ℃; for 16h; Reagent/catalyst;

Reference yield:

→ violuric acid (87-39-8)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01175a002

Reference yield:

alloxan-4-oxime (74646-24-5) → violuric acid (87-39-8)

Guidance literature:

With hydrogenchloride;

DOI:10.1073/pnas.18.7.490

upstream raw materials:

BARBITURIC ACID

n-Amyl nitrite

pyrimidine-2,4,5,6(1H,3H)-tetraone

uric Acid

Downstream raw materials:

1,3,6,8-tetrahydro-2,4,5,7-pyrimido<5,4-g>pteridinetetrone

riboflavin

uramil

5,5-dibromobarbituric acid

Refernces

• 1、 Illán-Cabeza, Nuria A.,García-García, Antonio R.,Moreno-Carretero, Miguel N.. "Complexes with 6-amino-5-nitroso-2-thiouracil and violuric acid derivatives containing the fac-ReI(CO)3 core: Synthesis, XRD structural and photoluminescence characterization". experimental part. p. 262 - 267. Retrieved 2011/04/12.