2-methylestradiol

Base Information

Chemical Name:2-methylestradiol
CAS No.:1818-12-8
Molecular Formula:C₁₉H₂₆O₂
Molecular Weight:286.414
Hs Code.:
Mol file:1818-12-8.mol

Synonyms:Estra-1,3,5(10)-triene-3,17b-diol, 2-methyl- (7CI,8CI);Estradiol, 2-methyl- (6CI); 2-Methyl-17b-estradiol; 2-Methylestra-1,3,5(10)-triene-3,17b-diol; 2-Methylestradiol; NSC666605

Suppliers and Price of 2-methylestradiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-MethylEstradiol
1g
$ 1320.00

TRC
2-MethylEstradiol17-Valerate
10mg
$ 1320.00

TRC
2-MethylEstradiol17-Valerate
1mg
$ 165.00

Total 11 raw suppliers

Chemical Property of 2-methylestradiol

Chemical Property:

Vapor Pressure:6.21E-09mmHg at 25°C
Boiling Point:451.3°Cat760mmHg
Flash Point:209.2°C
PSA：40.46000
Density:1.15g/cm³
LogP:3.91760

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-MethylEstradiol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An Estradiol (E888000) derivative as antitumor agent. A metabolite of Estradiol (E888000) as an antitumor agent.

Technology Process of 2-methylestradiol

There total 13 articles about 2-methylestradiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 96111-26-1
2-(N,N-dimethylamino)methylestrone

: 1818-12-8
2-Methyl-oestradiol

Guidance literature:: 2-(N,N-dimethylamino)methylestrone; With methyl iodide; In diethyl ether; at 20 ℃; for 24h;

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 18h; Further stages.;
DOI:10.1021/jm070405v

Reference yield: 33.0%

: 6599-97-9
2-formylestradiol

: 1818-12-8
2-Methyl-oestradiol

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; for 18h; under 2172.02 Torr; Ambient temperature;
DOI:10.1021/jm00012a003

Reference yield:

: 50-28-2
estradiol

: 1818-12-8
2-Methyl-oestradiol

Guidance literature:: Multi-step reaction with 2 steps

1: 24.8 percent / hexamethylenetetramine / 6 h / Heating

2: 33 percent / H₂ / 10percent Pd-C / ethanol; tetrahydrofuran / 18 h / 2172.02 Torr / Ambient temperature

With hexamethylenetetramine; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00012a003