Ethyl 1,6-dimethyl-4-(4-methylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Base Information

Chemical Name:Ethyl 1,6-dimethyl-4-(4-methylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS No.:887351-75-9
Molecular Formula:C₁₆H₂₀N₂O₃
Molecular Weight:288.346
Hs Code.:
Mol file:887351-75-9.mol

Synonyms:1,2,3,4-tetrahydro-1,6-dimethyl-4-(4-methylphenyl)-2-oxo-5-pyrimidinecarboxylic acid ethyl ester

Suppliers and Price of Ethyl 1,6-dimethyl-4-(4-methylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 1,6-dimethyl-4-(4-methylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate >95%
1g
$ 151.00

Crysdot
Ethyl1,6-dimethyl-2-oxo-4-(p-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate 95+%
10g
$ 357.00

Total 3 raw suppliers

Chemical Property of Ethyl 1,6-dimethyl-4-(4-methylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Chemical Property:

Melting Point:111-113°

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl 1,6-dimethyl-4-(4-methylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ethyl 1,6-dimethyl-4-(4-methylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

There total 2 articles about Ethyl 1,6-dimethyl-4-(4-methylphenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 589-18-4
4-Methylbenzyl alcohol

: 141-97-9
ethyl acetoacetate

: 598-50-5
N-Methylurea

: 887351-75-9
1,2,3,4-tetrahydro-1,6-dimethyl-4-(4-methylphenyl)-2-oxo-5-pyrimidinecarboxylic acid ethyl ester

Guidance literature:: 4-Methylbenzyl alcohol; With Oxone; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; In neat (no solvent); for 0.5h; Milling; Green chemistry;

ethyl acetoacetate; N-Methylurea; In neat (no solvent); for 3h; regioselective reaction; Milling; Green chemistry;
DOI:10.1002/ejoc.201501039

Reference yield: 86.0%

: 104-87-0
4-methyl-benzaldehyde

: 141-97-9
ethyl acetoacetate

: 598-50-5
N-Methylurea

: 887351-75-9
1,2,3,4-tetrahydro-1,6-dimethyl-4-(4-methylphenyl)-2-oxo-5-pyrimidinecarboxylic acid ethyl ester

Guidance literature:: With aluminium-planted mesoporous silica M₄₁ with Si/Al = 33; In octane; at 114.84 ℃; for 10h; Inert atmosphere;
DOI:10.1039/b920821f