methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside

Base Information

Chemical Name:methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside
CAS No.:110045-94-8
Molecular Formula:C₃₃H₃₈O₇
Molecular Weight:546.661
Hs Code.:

Synonyms:methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside

Suppliers and Price of methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside

There total 8 articles about methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110045-93-7
Benzoic acid (2R,3R,4S,5R,6S)-4,5-bis-benzyloxy-2-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-but-3-enyl]-6-methoxy-tetrahydro-pyran-3-yl ester

: 110045-94-8
methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside

Guidance literature:: With camphor-10-sulfonic acid; In methanol; for 20h; Yield given; Ambient temperature;
DOI:10.1021/jo00229a015

Reference yield:

: 98-88-4
benzoyl chloride

: 110045-94-8
methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 16 h / 40 °C

2: thionyl chloride / pyridine / 0.08 h / 0 °C

3: dl-camphorsulfonic acid / methanol / 20 h / Ambient temperature

With pyridine; thionyl chloride; camphor-10-sulfonic acid; In pyridine; methanol;
DOI:10.1021/jo00229a015

Reference yield:

: 110045-79-9
methyl-(1) 3,4-dimethoxybenzyl-(8)(8R)-2,3-di-O-benzyl-6-deoxy-6-C-methyl-β-L-threo-D-gluco-octodialdo-1,5:8,4-dipyranoside

: 110045-94-8
methyl 4-O-benzoyl-2,3-di-O-benzyl-6,8,9-trideoxy-6,8-di-C-methyl-7-O-(tert-butyldimethylsilyl)-L-threo-α-D-gluco-non-8-eno-1,5-pyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: triethylamine, 4-(dimethylamino)pyridine / CH₂Cl₂ / 16 h / Ambient temperature

2: 2,3-dichloro,5,6-dicyano-1,4-benzoquinone / CH₂Cl₂; dioxane; H₂O / 4 h / Ambient temperature

3: pyridinium chlorochromate, Celite, Florisil, sodium acetate / CH₂Cl₂ / Ambient temperature

4: 94 percent / tetrahydrofuran / 1 h / Ambient temperature

5: pyridine / 16 h / 40 °C

6: thionyl chloride / pyridine / 0.08 h / 0 °C

7: dl-camphorsulfonic acid / methanol / 20 h / Ambient temperature

With pyridine; dmap; florisil; thionyl chloride; Celite; camphor-10-sulfonic acid; sodium acetate; triethylamine; pyridinium chlorochromate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; 1,4-dioxane; pyridine; methanol; dichloromethane; water;
DOI:10.1021/jo00229a015