methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside

Base Information

• Chemical Name: methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside
• CAS No.: 80596-05-0
• Molecular Formula: C₅₇H₆₂O₁₂
• Molecular Weight: 939.112
• Mol file: 80596-05-0.mol

Synonyms:methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside

Chemical Property of methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside

There total 13 articles about methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl 3,4,6-tri-O-benzyl-α-D-mannopyranoside (20672-67-7) + phenyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside (138181-67-6,127299-78-9) → methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside (80596-05-0)

Guidance literature:

methyl 3,4,6-tri-O-benzyl-α-D-mannopyranoside; phenyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside; With N-(p-methylphenylthio)-ε-caprolactam; In dichloromethane; at 0 - 20 ℃; for 0.583333h; Molecular sieve; Inert atmosphere;

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃; for 0.5h; Inert atmosphere; Molecular sieve;

DOI:10.1055/s-0032-1316685

Reference yield: 92.0%

methyl 3,4,6-tri-O-benzyl-α-D-mannopyranoside (20672-67-7) + 2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl trichloroacetimidate (108869-64-3,130177-78-5,129163-12-8) → methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside (80596-05-0)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -5 ℃; for 1h; Inert atmosphere; Molecular sieve;

Reference yield: 88.0%

methyl 3,4,6-tri-O-benzyl-α-D-mannopyranoside (20672-67-7) + C29H34O6S → methyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside (80596-05-0)

Guidance literature:

With N-iodo-succinimide; trifluorormethanesulfonic acid; In dichloromethane; at 0 ℃; for 0.5h; Molecular sieve; Inert atmosphere;

DOI:10.1016/j.tetlet.2008.07.089

upstream raw materials:

methyl 3,4,6-tri-O-benzyl-α-D-mannopyranoside

2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl chloride

2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl bromide

ethyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside

Downstream raw materials:

methyl O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1<*>2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside