Benzenemethanamine, 4-fluoro-.alpha.-methyl-3-(4-morpholinyl)-, (.alpha.S)-

Base Information

Chemical Name:Benzenemethanamine, 4-fluoro-.alpha.-methyl-3-(4-morpholinyl)-, (.alpha.S)-
CAS No.:591742-65-3
Molecular Formula:C₁₂H₁₇FN₂O
Molecular Weight:224.278
Hs Code.:
Mol file:591742-65-3.mol

Synonyms:(S)-1-(4-fluoro-3-morpholin-4-yl-phenyl)ethylamine

Suppliers and Price of Benzenemethanamine, 4-fluoro-.alpha.-methyl-3-(4-morpholinyl)-, (.alpha.S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

American Custom Chemicals Corporation
BENZENEMETHANAMINE, 4-FLUORO-.ALPHA.-METHYL-3-(4-MORPHOLINYL)-, (.ALPHA.S)- 95.00%
5MG
$ 502.65

Total 0 raw suppliers

Chemical Property of Benzenemethanamine, 4-fluoro-.alpha.-methyl-3-(4-morpholinyl)-, (.alpha.S)-

Chemical Property:

Purity/Quality:: BENZENEMETHANAMINE, 4-FLUORO-.ALPHA.-METHYL-3-(4-MORPHOLINYL)-, (.ALPHA.S)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzenemethanamine, 4-fluoro-.alpha.-methyl-3-(4-morpholinyl)-, (.alpha.S)-

There total 4 articles about Benzenemethanamine, 4-fluoro-.alpha.-methyl-3-(4-morpholinyl)-, (.alpha.S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 591742-64-2
[(S)-1-(4-Fluoro-3-morpholin-4-yl-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine

: 591742-65-3
(S)-1-(4-fluoro-3-morpholin-4-yl-phenyl)ethylamine

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol;
DOI:10.1016/S0960-894X(03)00240-3

Reference yield:

: 1007-15-4
4-fluoro-3-bromoacetophenone

: 591742-65-3
(S)-1-(4-fluoro-3-morpholin-4-yl-phenyl)ethylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 79 percent / Pd(OAc)2; Cs₂CO₃; di(tert-butyl)(2-biphenyl)phosphine / benzene / 17 h / 80 °C

2: TiCl₄; Et₃N / toluene / 12 h

3: H₂ / Ra-Ni / methanol / 2 h / 1551.44 Torr

4: HCOONH₄ / Pd/C / methanol

With palladium diacetate; hydrogen; ammonium formate; titanium tetrachloride; caesium carbonate; triethylamine; johnphos; palladium on activated charcoal; Ra-Ni; In methanol; toluene; benzene;
DOI:10.1016/S0960-894X(03)00240-3

Reference yield:

: 519137-75-8
1-(4-fluoro-3-morpholin-4-yl-phenyl)-ethanone

: 591742-65-3
(S)-1-(4-fluoro-3-morpholin-4-yl-phenyl)ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: TiCl₄; Et₃N / toluene / 12 h

2: H₂ / Ra-Ni / methanol / 2 h / 1551.44 Torr

3: HCOONH₄ / Pd/C / methanol

With hydrogen; ammonium formate; titanium tetrachloride; triethylamine; palladium on activated charcoal; Ra-Ni; In methanol; toluene;
DOI:10.1016/S0960-894X(03)00240-3