(1R,2S)-1-phenoxy-1-phenylpropan-2-ol

Base Information

Chemical Name:(1R,2S)-1-phenoxy-1-phenylpropan-2-ol
CAS No.:1241959-81-8
Molecular Formula:C₁₅H₁₆O₂
Molecular Weight:228.291
Hs Code.:

Synonyms:(1R,2S)-1-phenoxy-1-phenylpropan-2-ol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2S)-1-phenoxy-1-phenylpropan-2-ol

Chemical Property:

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Technology Process of (1R,2S)-1-phenoxy-1-phenylpropan-2-ol

There total 4 articles about (1R,2S)-1-phenoxy-1-phenylpropan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 35855-75-5
1-phenoxy-1-phenylpropan-2-one

: 1241959-81-8
(1R,2S)-1-phenoxy-1-phenylpropan-2-ol

Guidance literature:: With RuCl₂-(S)-SDP/(R,R)-DPEN; potassium tert-butylate; hydrogen; In isopropyl alcohol; at 25 - 30 ℃; for 12h; under 7600.51 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;
DOI:10.1002/adsc.200900675

Reference yield:

: C₂₂H₂₂O₂

: 1241959-81-8
(1R,2S)-1-phenoxy-1-phenylpropan-2-ol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; at 20 ℃; under 2585.81 Torr;
DOI:10.1016/j.bmc.2021.116455

Reference yield:

: 114418-34-7
(1R,2S)-2-Benzyloxy-1-phenyl-propan-1-ol

: 1241959-81-8
(1R,2S)-1-phenoxy-1-phenylpropan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: copper diacetate / dichloromethane / 20 °C

2: hydrogen; palladium 10% on activated carbon / 20 °C / 2585.81 Torr

With palladium 10% on activated carbon; hydrogen; copper diacetate; In dichloromethane;
DOI:10.1016/j.bmc.2021.116455