5-(2-(6-(N^α-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP

Base Information

Chemical Name:5-(2-(6-(N^α-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP
CAS No.:885109-37-5
Molecular Formula:C₃₅H₄₈N₅O₁₉P₃
Molecular Weight:935.71
Hs Code.:

5-(2-(6-(N<sup>α</sup>-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP

Synonyms:5-(2-(6-(N^α-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP

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Chemical Property of 5-(2-(6-(N^α-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP

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Technology Process of 5-(2-(6-(N^α-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP

There total 2 articles about 5-(2-(6-(N^α-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 98647-23-5
O-benzyl-N^α-benzyloxycarbonylserine succinimidyl ester

: 5-(2-(6-aminohexylamino)-2-oxoethyl)-2'-deoxyuridine 5'-triphosphate

: 885109-37-5
5-(2-(6-(N^α-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP

Guidance literature:: With sodium hydrogencarbonate; In water; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmc.2005.11.030

Reference yield:

: 20806-43-3
Z-Ser(Bzl)-OH

: 885109-37-5
5-(2-(6-(N^α-carbobenzoxy-O-benzyl-L-serinamido)hexylamino)-2-oxoethyl)-2'-dUTP

Guidance literature:: Multi-step reaction with 2 steps

1: N,N'-dicyclohexylcarbodiimide / dimethylformamide / 0 - 20 °C

2: 54 percent / NaHCO₃ / dimethylformamide; H₂O / 20 °C

With sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2005.11.030