Technology Process of C20H22FNO6
There total 6 articles about C20H22FNO6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tris(acetoxy)borohydride; acetic acid;
at -4 ℃;
for 1h;
DOI:10.1021/ja312148q
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydrogencarbonate / tetrahydrofuran / 1.3 h / 0 - 20 °C
2: silver(II) sulfate; iodine / acetonitrile / 0.67 h / -20 °C
3: triphenyl-arsane; palladium diacetate; tributyl-amine / N,N-dimethyl-formamide / 15 h / 20 - 70 °C / Inert atmosphere
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 20 °C
5: acetic acid; sodium tris(acetoxy)borohydride / 1 h / -4 °C
With
silver(II) sulfate; tributyl-amine; triphenyl-arsane; tetrabutyl ammonium fluoride; iodine; palladium diacetate; sodium tris(acetoxy)borohydride; sodium hydrogencarbonate; acetic acid;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
3: |Heck Reaction;
DOI:10.1021/ja312148q
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydrogencarbonate / tetrahydrofuran / 1.3 h / 0 - 20 °C
2: silver(II) sulfate; iodine / acetonitrile / 0.67 h / -20 °C
3: triphenyl-arsane; palladium diacetate; tributyl-amine / N,N-dimethyl-formamide / 15 h / 20 - 70 °C / Inert atmosphere
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 20 °C
5: acetic acid; sodium tris(acetoxy)borohydride / 1 h / -4 °C
With
silver(II) sulfate; tributyl-amine; triphenyl-arsane; tetrabutyl ammonium fluoride; iodine; palladium diacetate; sodium tris(acetoxy)borohydride; sodium hydrogencarbonate; acetic acid;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
3: |Heck Reaction;
DOI:10.1021/ja312148q