Ampyrimine

Base Information

Chemical Name:Ampyrimine
CAS No.:5587-93-9
Molecular Formula:C₁₂H₁₁N₇
Molecular Weight:253.266
Hs Code.:
UNII:X26VF7L4AL
DSSTox Substance ID:DTXSID00204465
Wikidata:Q27293400
NCI Thesaurus Code:C81072
ChEMBL ID:CHEMBL2107705
Mol file:5587-93-9.mol

Synonyms:Ampyrimine;5587-93-9;Ampyrimine [INN];Ampyrimina;Ampyriminum;SKF 13338;UNII-X26VF7L4AL;X26VF7L4AL;SKF-13338;Pyrimido(4,5-d)pyrimidine, 2,4,7-triamino-5-phenyl-;2,4,7-Triamino-5-phenylpyrimido(4,5-d)pyrimidin;2,4,7-Triamino-5-phenylpyrimido(4,5-d)pyrimidine;Pyrimido[4,5-d]pyrimidine, 2,4,7-triamino-5-phenyl-;5-phenylpyrimido[4,5-d]pyrimidine-2,4,7-triamine;SCHEMBL1230765;CHEMBL2107705;Pyrimido[4,5-d]pyrimidine-2,4,7-triamine, 5-phenyl-;DTXSID00204465;AKOS040750499;Q27293400

Suppliers and Price of Ampyrimine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,4,7-TRIAMINO-5-PHENYLPYRIMIDO[4,5-D]PYRIMIDINE 95.00%
5MG
$ 503.54

Total 3 raw suppliers

Chemical Property of Ampyrimine

Chemical Property:

Vapor Pressure:4.08E-17mmHg at 25°C
Boiling Point:656.6°Cat760mmHg
Flash Point:388.7°C
Density:1.502g/cm³
XLogP3:0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:253.10759338
Heavy Atom Count:19
Complexity:307

Purity/Quality:: 2,4,7-TRIAMINO-5-PHENYLPYRIMIDO[4,5-D]PYRIMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C3C(=NC(=NC3=NC(=N2)N)N)N

Technology Process of Ampyrimine

There total 5 articles about Ampyrimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42754-56-3
2-(methoxyphenylmethylene)malononitrile

: 5587-93-9
2,5,7-Triamino-4-phenylpyrimido<4,5-d>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / methanol / Heating

2: C₂H₅ONa / EtOH, 1.) ice-cooling, 30 min, 2.) 20 h, reflux

With sodium ethanolate; In methanol;
DOI:10.1055/s-1981-29654

Reference yield:

: 14533-93-8
Methyl (E)-2-cyano-3-methoxy-3-phenylpropenoate

: 5587-93-9
2,5,7-Triamino-4-phenylpyrimido<4,5-d>pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 54 percent / ethanol / 2 h / Heating

2: 80 percent / diethyl ether; ethyl acetate / 0.5 h

3: C₂H₅ONa / EtOH, 1.) ice-cooling, 30 min, 2.) 20 h, reflux

With sodium ethanolate; In diethyl ether; ethanol; ethyl acetate;
DOI:10.1055/s-1981-29654

Reference yield:

: 81066-94-6
2-amino-1,6-dihydro-6-oxo-4-phenylpyrimidine-5-carbonitrile

: 5587-93-9
2,5,7-Triamino-4-phenylpyrimido<4,5-d>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / diethyl ether; ethyl acetate / 0.5 h

2: C₂H₅ONa / EtOH, 1.) ice-cooling, 30 min, 2.) 20 h, reflux

With sodium ethanolate; In diethyl ether; ethyl acetate;
DOI:10.1055/s-1981-29654