diethyl cyclohexylidensuccinate

Base Information

• Chemical Name: diethyl cyclohexylidensuccinate
• CAS No.: 124209-98-9
• Molecular Formula: C₁₄H₂₂O₄
• Molecular Weight: 254.326
• Mol file: 124209-98-9.mol

Synonyms:diethyl cyclohexylidensuccinate

Chemical Property of diethyl cyclohexylidensuccinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of diethyl cyclohexylidensuccinate

There total 4 articles about diethyl cyclohexylidensuccinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + succinic acid diethyl ester (123-25-1) → diethyl cyclohexylidensuccinate (124209-98-9)

Guidance literature:

cyclohexanone; succinic acid diethyl ester; With potassium tert-butylate; In tert-butyl alcohol; at 15 ℃; for 1.5h;

With sulfuric acid; In ethanol; at 0 - 20 ℃; for 48h;

DOI:10.1055/s-2005-917082

Reference yield: 40.0%

diethyl cyclohex-1-enylsuccinate (71932-44-0) → diethyl cyclohexylidensuccinate (124209-98-9) + ethyl 2-oxo-1-oxaspiro<4,5>decane-4-carboxylate (61858-03-5)

Guidance literature:

With sulfuric acid;

DOI:10.1055/s-2005-917082

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → diethyl cyclohexylidensuccinate (124209-98-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / tetrahydrofuran / 16 h / 0 - 20 °C

1.2: 72 percent / H₂SO₄ / ethanol / 18 h / 80 °C

2.1: 9 percent / H₂SO₄

With sulfuric acid; sodium hydride; In tetrahydrofuran;

DOI:10.1055/s-2005-917082

upstream raw materials:

diethyl cyclohex-1-enylsuccinate

cyclohexanone

succinic acid diethyl ester

Downstream raw materials:

(1-methyl-2-indolylmethyl)-1-cyclohexenylmaleic anhydride

3-Cyclohexylidene-4-[1-(2,5-dimethyl-thiophen-3-yl)-eth-(Z)-ylidene]-dihydro-furan-2,5-dione

2-Cyclohexylidene-3-[1-(2,5-dimethyl-thiophen-3-yl)-eth-(Z)-ylidene]-succinic acid

E-(1,2-Dimethyl-3-indolylmethylene)cyclohexylidenesuccinic Acid