N-hydroxyquinoline-2-carboxamide

Base Information

Chemical Name:N-hydroxyquinoline-2-carboxamide
CAS No.:37137-42-1
Molecular Formula:C10H8 N2 O2
Molecular Weight:188.186
Hs Code.:2933499090
European Community (EC) Number:867-893-4
DSSTox Substance ID:DTXSID70190624
Nikkaji Number:J2.257.866I
Wikidata:Q83063014
Pharos Ligand ID:MWB6MW4PU2ZP
ChEMBL ID:CHEMBL3798481
Mol file:37137-42-1.mol

Synonyms:N-hydroxyquinoline-2-carboxamide;37137-42-1;N-Hydroxy-2-quinolinecarboxamide;Quinaldinohydroxamic acid;2-Quinolinecarboxamide, N-hydroxy-;Quinoline-2-carbohydroxamic acid;2-Quinolinecarboxamide,N-hydroxy-;BRN 0148428;CHEMBL3798481;5-22-03-00190 (Beilstein Handbook Reference);VWG;quinolinecarbohydroxamic;quinolyl hydroximic acid;EC-000.1745;Oprea1_434332;2-Quinolinecarbohydroximic acid;SCHEMBL7010475;SCHEMBL18530693;DTXSID70190624;BDBM50164660;AKOS000186816;Quinoline-2-carboxylic acid hydroxyamide;LS-141448;CS-0265270;EN300-97387;F81269;Z59181945

Suppliers and Price of N-hydroxyquinoline-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-hydroxyquinoline-2-carboxamide
50mg
$ 155.00

American Custom Chemicals Corporation
N-HYDROXY-2-QUINOLINECARBOXAMIDE 95.00%
5MG
$ 495.58

AK Scientific
N-Hydroxyquinoline-2-carboxamide
10g
$ 2748.00

Total 6 raw suppliers

Chemical Property of N-hydroxyquinoline-2-carboxamide

Chemical Property:

Melting Point:136 °C (decomp)
Boiling Point:°Cat760mmHg
PKA:7.71±0.30(Predicted)
Flash Point:°C
PSA：62.22000
Density:1.362g/cm³
LogP:1.74470
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:188.058577502
Heavy Atom Count:14
Complexity:220

Purity/Quality:

99% ^*data from raw suppliers

N-hydroxyquinoline-2-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC(=N2)C(=O)NO

Technology Process of N-hydroxyquinoline-2-carboxamide

There total 16 articles about N-hydroxyquinoline-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 135709-62-5
methyl quinoline-2-carboxylate hydrochloride

: 37137-42-1
quinaldic hydroxamic acid

Guidance literature:: methyl quinoline-2-carboxylate hydrochloride; With potassium hydroxide; In methanol; for 0.25h; Inert atmosphere; Cooling with ice;

With hydroxylamine; In methanol; at 20 ℃; for 96h; Inert atmosphere;
DOI:10.1021/ic302831u

Reference yield: 72.0%

: 19575-07-6
quinoline-2-carboxylic acid methyl ester

: 37137-42-1
N-hydroxy-2-quinolinecarboxamide

Guidance literature:: With hydroxylamine hydrochloride; sodium methylate; In methanol; for 48h; Ambient temperature;
DOI:10.1007/BF00799961

Reference yield: 58.2%

: 93-10-7,1199266-78-8
quinoline-2-carboxylic acid

: 37137-42-1
N-hydroxy-2-quinolinecarboxamide

Guidance literature:: quinoline-2-carboxylic acid; With 4-methyl-morpholine; chloroformic acid ethyl ester; In dichloromethane; at 0 ℃; for 0.333333h;

With hydroxylamine hydrochloride; In methanol; dichloromethane; at 0 - 20 ℃; for 1.5h;