evomonoside α-L-rhamnopyranoside tribenzoate

Base Information

• Chemical Name: evomonoside α-L-rhamnopyranoside tribenzoate
• CAS No.: 144879-84-5
• Molecular Formula: C₅₀H₅₆O₁₁
• Molecular Weight: 832.988
• Mol file: 144879-84-5.mol

Synonyms:evomonoside α-L-rhamnopyranoside tribenzoate

Chemical Property of evomonoside α-L-rhamnopyranoside tribenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of evomonoside α-L-rhamnopyranoside tribenzoate

There total 2 articles about evomonoside α-L-rhamnopyranoside tribenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4-tri-O-benzoyl-α-L-rhamnopyranosyltrichloroacetimidate (161007-95-0) + (+)-digitoxigenin (143-62-4) → evomonoside α-L-rhamnopyranoside tribenzoate (144879-84-5)

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; at 0 - 20 ℃; for 5h; diastereoselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1021/jacs.8b12870

Reference yield:

2,3,4-tri-O-benzoyl-α-L-rhamnopyranosyl bromide (14218-08-7,41881-44-1,53297-33-9,60820-93-1,61198-82-1,67986-91-8,73068-86-7,131897-72-8,131897-73-9) + (+)-digitoxigenin (143-62-4) → evomonoside α-L-rhamnopyranoside tribenzoate (144879-84-5)

Guidance literature:

With mercury(II) cyanide; In 1,2-dichloro-ethane; for 3h;

Reference yield: 75.0%

evomonoside α-L-rhamnopyranoside tribenzoate (144879-84-5) → digitoxigenin 3-(α-L-rhamnopyranoside) (508-93-0)

Guidance literature:

With ammonium hydroxide; In methanol; for 16h; Ambient temperature;

DOI:10.1021/jm00053a006

upstream raw materials:

2,3,4-tri-O-benzoyl-α-L-rhamnopyranosyl bromide

(+)-digitoxigenin

2,3,4-tri-O-benzoyl-α-L-rhamnopyranosyltrichloroacetimidate

Downstream raw materials:

digitoxigenin 3-(α-L-rhamnopyranoside)

3β-(tri-O-benzoyl-α-L-rhamnopyranosyloxy)-5β,14β-pregnane-14,20β-diol

14-hydroxy-3β-(tri-O-benzoyl-α-L-rhamnopyranosyloxy)-5β,14β-pregnan-20-one

3-<(tri-O-benzoyl-α-L-rhamnopyranosyl)oxy>-17β-(hydroxymethyl)-5β-androstane-3β,14β-diol