methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate

Base Information

Chemical Name:methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate
CAS No.:304682-65-3
Molecular Formula:C₂₀H₂₉N₃O₆
Molecular Weight:407.467
Hs Code.:

Synonyms:methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate

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Chemical Property of methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate

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Technology Process of methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate

There total 1 articles about methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 5680-79-5,883886-67-7
glycine ethyl ester hydrochloride

: 266338-75-4
2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methylpropanoic acid

: 304682-65-3
methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate

Guidance literature:: With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In acetonitrile; at 20 ℃; for 15h;
DOI:10.1002/1522-2675(20000809)83:8<1881::AID-HLCA1881>3.0.CO;2-G

Reference yield: 91.0%

: 304682-65-3
methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate

: 304682-66-4
2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 19h;
DOI:10.1002/1522-2675(20000809)83:8<1881::AID-HLCA1881>3.0.CO;2-G

Reference yield: 74.0%

: 2133-40-6
L-proline methyl ester monohydrochloride

: 304682-65-3
methyl 2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}ethanoate

: 304682-69-7
methyl (S)-1-(2-{[2-({2-[(3-hydroxy-1-oxo-2-phenylpropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-1-oxoethyl)pyrrolidine-2-carboxylate

Guidance literature:: With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In acetonitrile; at 20 ℃; for 17h;
DOI:10.1002/1522-2675(20000809)83:8<1881::AID-HLCA1881>3.0.CO;2-G