Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester

Base Information

Chemical Name:Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester
CAS No.:143465-53-6
Molecular Formula:C₃₅H₅₄NO₁₀P
Molecular Weight:679.788
Hs Code.:

Synonyms:Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester

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Chemical Property of Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester

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Technology Process of Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester

There total 11 articles about Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143465-52-5
Phosphoric acid (1S,2R,3R,4R,5R)-3,4-bis-benzyloxy-5-benzyloxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester

: 143465-53-6
Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester

Guidance literature:: With hydrogen; palladium dihydroxide; In tetrahydrofuran; methanol;
DOI:10.1016/0040-4039(92)80009-9

Reference yield:

: 87357-65-1
(3R)-3-hydroxytetradecanoic acid phenacyl ester

: 143465-53-6
Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: diisopropylethylamine

2: Zn dust / acetic acid

3: 92 percent / DCC / CH₂Cl₂

4: H₂ / 20percent Pd(OH)2 / tetrahydrofuran; methanol

With hydrogen; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; zinc; palladium dihydroxide; In tetrahydrofuran; methanol; dichloromethane; acetic acid;
DOI:10.1016/0040-4039(92)80009-9

Reference yield:

: 143465-57-0
(R)-3-methoxymethyloxytetradecanoic acid

: 143465-53-6
Phosphoric acid (1S,2R,3R,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-2-((R)-3-methoxymethoxy-tetradecanoylamino)-cyclohexyl ester diphenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / DCC / CH₂Cl₂

2: H₂ / 20percent Pd(OH)2 / tetrahydrofuran; methanol

With hydrogen; dicyclohexyl-carbodiimide; palladium dihydroxide; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/0040-4039(92)80009-9