2,6-dimethyl-1-oxo-6H-pyridin-4-amine

Base Information

• Chemical Name: 2,6-dimethyl-1-oxo-6H-pyridin-4-amine
• CAS No.: 3512-82-1
• Molecular Formula: C7H10N2O
• Molecular Weight: 138.1671
• Hs Code.: 2933399090
• Mol file: 3512-82-1.mol

Synonyms:2,6-dimethyl-1-oxy-pyridin-4-ylamine;4-Amino-2,6-dimethylpyridin-1-oxid;4-amino-2,6-dimethylpyridine 1-oxide;2,6-Dimethyl-4-pyridinamine 1-oxide;2,6-Dimethyl-1-oxy-[4]pyridylamin;2,6-dimethyl-1-oxy-[4]pyridylamine;4-Amino-2,6-lutidin-1-oxid;

Chemical Property of 2,6-dimethyl-1-oxo-6H-pyridin-4-amine

Chemical Property:

• Boiling Point: 229.6°Cat760mmHg
• Flash Point: 92.7°C
• PSA: 51.48000
• Density: 1.15g/cm³
• LogP: 1.89530

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-AMINO-2,6-DIMETHYLPYRIDINE-1-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-dimethyl-1-oxo-6H-pyridin-4-amine

There total 2 articles about 2,6-dimethyl-1-oxo-6H-pyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-2,6-lutidine-1-oxide (4808-64-4) → 4-amino-2,6-dimethylpyridine 1-oxide (3512-82-1)

Guidance literature:

With palladium on activated charcoal; water;

Reference yield:

→ 4-amino-2,6-dimethylpyridine 1-oxide (3512-82-1)

Guidance literature:

4-Nitro-2,6-dimethyl-pyridin-1-oxid, H2 an Pd;

Reference yield:

4-amino-2,6-dimethylpyridine 1-oxide (3512-82-1) → 2-[(2,4-dimethoxybenzyl)thio]-N-(2,6-dimethyl-4-pyridinyl)pyridine-3-carboxamide

Guidance literature:

Multi-step reaction with 2 steps

2: 71 percent / PCl₃ / CH₂Cl₂ / 0.5 h / Heating

With phosphorus trichloride; In dichloromethane;

DOI:10.1248/cpb.45.1027

upstream raw materials:

4-nitro-2,6-lutidine-1-oxide

Downstream raw materials:

2-(2,4-Dimethoxy-benzylsulfanyl)-N-(2-hydroxymethyl-6-methyl-pyridin-4-yl)-nicotinamide

2-[(2,4-dimethoxybenzyl)thio]-N-(6-methyl-2-propionyloxymethyl-4-pyridinyl)pyridine-3-carboxamide