1-(4-Nitrophenyl)-3-phenylurea

Base Information

• Chemical Name: 1-(4-Nitrophenyl)-3-phenylurea
• CAS No.: 1932-32-7
• Molecular Formula: C13H11 N3 O3
• Molecular Weight: 257.249
• European Community (EC) Number: 667-633-8
• NSC Number: 32359
• DSSTox Substance ID: DTXSID30283602
• Wikidata: Q82018231
• Mol file: 1932-32-7.mol

Synonyms:1-(4-nitrophenyl)-3-phenylurea;1932-32-7;3-(4-nitrophenyl)-1-phenylurea;N-(4-nitrophenyl)-N'-phenylurea;N-(4-Nitrophenyl)-N'-phenyl-urea;Urea, N-(4-nitrophenyl)-N'-phenyl-;NSC32359;SCHEMBL11055960;DTXSID30283602;QHHPMKKJBURYIQ-UHFFFAOYSA-N;BAA93232;1-(4-nitrophenyl)-3-(phenyl)urea;N-(4-nitrophenyl)-N' -phenyl urea;NSC-32359;AKOS003409565;EN300-156184

Chemical Property of 1-(4-Nitrophenyl)-3-phenylurea

Chemical Property:

• Vapor Pressure: 9.28E-05mmHg at 25°C
• Boiling Point: 339.3°Cat760mmHg
• Flash Point: 159°C
• Density: 1.415g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 257.08004122
• Heavy Atom Count: 19
• Complexity: 316

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 1-(4-Nitrophenyl)-3-phenylurea

There total 40 articles about 1-(4-Nitrophenyl)-3-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

p-nitrobenzene iodide (636-98-6) + phenyl carbamate (64-10-8) → N-(4-nitrophenyl)-N'-phenylurea (1932-32-7)

Guidance literature:

With potassium phosphate; copper(l) iodide; N,N`-dimethylethylenediamine; In N,N-dimethyl-formamide; at 85 ℃; for 18h;

DOI:10.1016/j.cclet.2010.12.018

Reference yield: 94.0%

4-Nitrophenyl isocyanate (100-28-7) + aniline (62-53-3) → N-(4-nitrophenyl)-N'-phenylurea (1932-32-7)

Guidance literature:

In toluene; at 20 ℃; Inert atmosphere;

DOI:10.1039/c5ce00213c

Reference yield: 93.0%

N-(4-nitrophenyl)-N'-phenylthiourea (7669-49-0) → N-(4-nitrophenyl)-N'-phenylurea (1932-32-7)

Guidance literature:

With potassium superoxide; In dimethyl sulfoxide; for 8h; Ambient temperature;

DOI:10.1246/cl.1984.309

upstream raw materials:

4-Nitrophenyl isocyanate

aniline

toluene

benzene

Downstream raw materials:

bis-N,N'-(4-nitrophenyl)urea

3-(4-nitrophenyl)-1-phenyl-1-nitrosourea