methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate

Base Information

Chemical Name:methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate
CAS No.:1445790-85-1
Molecular Formula:C₂₁H₂₀BrN₃O₄
Molecular Weight:458.311
Hs Code.:

Synonyms:methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate

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Chemical Property of methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate

Chemical Property:

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Technology Process of methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate

There total 4 articles about methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: methyl 3-amino-5-isopropoxybenzoate

: 1374867-81-8
7-bromo-4-chloroquinoline-3-carboxamide

: 1445790-85-1
methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate

Guidance literature:: With acetic acid; at 20 ℃; for 1h;

Reference yield:

: 55076-32-9
methyl 3-hydroxy-5-nitrobenzoate

: 1445790-85-1
methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / N,N-dimethyl-formamide / 2.5 h / 120 °C

2: hydrogen; palladium 10% on activated carbon / ethanol / 16 h / 20 °C

3: acetic acid / 1 h / 20 °C

With palladium 10% on activated carbon; hydrogen; caesium carbonate; acetic acid; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 1375150-07-4
methyl 3-[(1-methylethyl)oxy]-5-nitrobenzoate

: 1445790-85-1
methyl 3-((7-bromo-3-carbamoylquinolin-4-yl)amino)-5-isopropoxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen; palladium 10% on activated carbon / ethanol / 16 h / 20 °C

2: acetic acid / 1 h / 20 °C

With palladium 10% on activated carbon; hydrogen; acetic acid; In ethanol;