N₂-isobutyryl-1,N₂-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)

Base Information

• Chemical Name: N₂-isobutyryl-1,N₂-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)
• CAS No.: 1256294-82-2
• Molecular Formula: C₅₄H₆₈N₇O₁₂P
• Molecular Weight: 1038.15

Synonyms:N₂-isobutyryl-1,N₂-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)

Chemical Property of N₂-isobutyryl-1,N₂-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)

Chemical Property:

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Technology Process of N₂-isobutyryl-1,N₂-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)

There total 1 articles about N₂-isobutyryl-1,N₂-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite (102691-36-1) + N2-isobutyryl-1,N2-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine (112154-53-7) → N2-isobutyryl-1,N2-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite) (1256294-82-2)

Guidance literature:

With 1H-tetrazole; diisopropylamine; In dichloromethane; at 20 ℃; for 14h;

DOI:10.3390/molecules15117509

upstream raw materials:

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite

N₂-isobutyryl-1,N₂-[1,2-di(isobutyryloxy)ethylene]-3',5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine

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