Benzenamine, 4-((3-(1,3,4,6,11,11a-hexahydro-2H-pyrazino(1,2-b)isoquinolin-2-yl)propyl)sulfonyl)-

Base Information

Chemical Name:Benzenamine, 4-((3-(1,3,4,6,11,11a-hexahydro-2H-pyrazino(1,2-b)isoquinolin-2-yl)propyl)sulfonyl)-
CAS No.:115041-59-3
Molecular Formula:C21H27 N3 O2 S
Molecular Weight:385.53
Hs Code.:
DSSTox Substance ID:DTXSID30921597

Synonyms:BRN 5141266;115041-59-3;Benzenamine, 4-((3-(1,3,4,6,11,11a-hexahydro-2H-pyrazino(1,2-b)isoquinolin-2-yl)propyl)sulfonyl)-;C21H27N3O2S;DTXSID30921597;C21-H27-N3-O2-S;LS-28343;4-[3-(1,3,4,6,11,11a-Hexahydro-2H-pyrazino[1,2-b]isoquinolin-2-yl)propane-1-sulfonyl]aniline

Suppliers and Price of Benzenamine, 4-((3-(1,3,4,6,11,11a-hexahydro-2H-pyrazino(1,2-b)isoquinolin-2-yl)propyl)sulfonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenamine, 4-((3-(1,3,4,6,11,11a-hexahydro-2H-pyrazino(1,2-b)isoquinolin-2-yl)propyl)sulfonyl)-

Chemical Property:

Vapor Pressure:2.17E-15mmHg at 25°C
Boiling Point:621.9°Cat760mmHg
Flash Point:329.9°C
Density:1.3g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:385.18239829
Heavy Atom Count:27
Complexity:583

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CC3=CC=CC=C3CC2CN1CCCS(=O)(=O)C4=CC=C(C=C4)N

Technology Process of Benzenamine, 4-((3-(1,3,4,6,11,11a-hexahydro-2H-pyrazino(1,2-b)isoquinolin-2-yl)propyl)sulfonyl)-

There total 4 articles about Benzenamine, 4-((3-(1,3,4,6,11,11a-hexahydro-2H-pyrazino(1,2-b)isoquinolin-2-yl)propyl)sulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.3%

: 115041-56-0
1-(1,3,4,6,11,11a-hexahydro-2H-pyrazino<1,2-b>isoquinolin-2-yl)-3-(4-aminophenylsulphono)propane

: 115041-59-3
4-[3-(1,3,4,6,11,11a-Hexahydro-pyrazino[1,2-b]isoquinolin-2-yl)-propane-1-sulfonyl]-phenylamine

Guidance literature:: With hydrogenchloride; at 130 ℃;

Reference yield:

: 78234-11-4
γ-chloropropyl-4-acetamidophenyl sulphide

: 115041-59-3
4-[3-(1,3,4,6,11,11a-Hexahydro-pyrazino[1,2-b]isoquinolin-2-yl)-propane-1-sulfonyl]-phenylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / 1) KMnO₄, 2) H₂O₂ / aq. acetic acid / 1) 30 deg C, 4 h

2: 66 percent / NaI, Na₂CO₃ / dimethylformamide / 80 °C

3: 83.3 percent / 15percent HCl / 130 °C

With hydrogenchloride; potassium permanganate; dihydrogen peroxide; sodium carbonate; sodium iodide; In acetic acid; N,N-dimethyl-formamide;

Reference yield:

: 78234-18-1
γ-chloropropyl 4-acetamidophenyl sulphone

: 115041-59-3
4-[3-(1,3,4,6,11,11a-Hexahydro-pyrazino[1,2-b]isoquinolin-2-yl)-propane-1-sulfonyl]-phenylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / NaI, Na₂CO₃ / dimethylformamide / 80 °C

2: 83.3 percent / 15percent HCl / 130 °C

With hydrogenchloride; sodium carbonate; sodium iodide; In N,N-dimethyl-formamide;