2-Benzyl-5-methoxyphenylacetic Acid

Base Information

• Chemical Name: 2-Benzyl-5-methoxyphenylacetic Acid
• CAS No.: 77605-64-2
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.301
• Mol file: 77605-64-2.mol

Synonyms:2-Benzyl-5-methoxyphenylacetic Acid

Chemical Property of 2-Benzyl-5-methoxyphenylacetic Acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-Benzyl-5-methoxyphenylacetic Acid

There total 3 articles about 2-Benzyl-5-methoxyphenylacetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-Benzoyl-5-methoxyphenylacetic acid (77605-58-4) → 2-Benzyl-5-methoxyphenylacetic Acid (77605-64-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic acid; at 50 - 60 ℃; for 7h; under 2280 Torr;

DOI:10.1021/jm00140a016

Reference yield:

3-phenyl-6-methoxy-1H-indene (15101-69-6) → 2-Benzyl-5-methoxyphenylacetic Acid (77605-64-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 22 percent / concd H₂SO₄, K₂Cr₂O₇ / H₂O; benzene / 3 h / 55 °C

2: 72 percent / H₂ / 5percent Pd/C / acetic acid / 7 h / 50 - 60 °C / 2280 Torr

With potassium dichromate; sulfuric acid; hydrogen; palladium on activated charcoal; In water; acetic acid; benzene;

DOI:10.1021/jm00140a016

Reference yield:

→ 2-Benzyl-5-methoxyphenylacetic Acid (77605-64-2)

Guidance literature:

upstream raw materials:

2-Benzoyl-5-methoxyphenylacetic acid

3-phenyl-6-methoxy-1H-indene