N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside

Base Information

• Chemical Name: N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside
• CAS No.: 389089-41-2
• Molecular Formula: C₁₄H₁₈ClNO₇
• Molecular Weight: 347.752
• Mol file: 389089-41-2.mol

Synonyms:N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside

Chemical Property of N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside

There total 5 articles about N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-(4-chlorophenyl)acetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside (1356933-19-1) → N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside (389089-41-2)

Guidance literature:

With Aspergillus niger lipase AS Amano; Streptomyces rochei carboxylesterase; water; In dimethyl sulfoxide; at 40 ℃; for 5h; pH=7.2; chemoselective reaction; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1021/jo202123s

Reference yield:

C12H16ClNO6 (1356933-37-3) + acetyl chloride (75-36-5) → N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside (389089-41-2)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; at 25 ℃;

DOI:10.1021/jo202123s

Reference yield:

N-(4-chlorophenyl)-N-hydroxyacetamide (1503-91-9) → N-(4-chlorophenyl)acetohydroxamic acid β-D-glucopyranoside (389089-41-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol; water / 1 h / 25 °C

2: methanol; barium methoxide / 0 °C

With methanol; barium methoxide; potassium hydroxide; In ethanol; water;

DOI:10.1021/jo202123s

upstream raw materials:

N-(4-chlorophenyl)acetohydroxamic acid 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

C₁₂H₁₆ClNO₆

acetyl chloride

N-(4-chlorophenyl)-N-hydroxyacetamide