Acx53N3fxt

Base Information

Chemical Name:Acx53N3fxt
CAS No.:165115-78-6
Molecular Formula:C₁₉H₂₀F₂O₂
Molecular Weight:318.363
Hs Code.:
UNII:ACX53N3FXT

Synonyms:ACX53N3FXT;(2S)-2-(Benzyloxymethyl)-4-(2,4-difluorophenyl)pent-4-en-1-ol;2-(Benzyloxymethyl)-4-(2,4-difluorophenyl)pent-4-en-1-ol, (2S)-;2-((benzyloxy)methyl)-4-(2,4-difluorophenyl)pent-4-en-1-ol, (S)-;2,4-Difluoro-delta-methylene-beta-[(phenylmethoxy)methyl]benzenebutanol, (S);Benzenebutanol, 2,4-difluoro-delta-methylene-beta-[(phenylmethoxy)methyl]-, (S)-;165115-78-6

Suppliers and Price of Acx53N3fxt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Acx53N3fxt

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:318.14313620
Heavy Atom Count:23
Complexity:355

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=C(CC(CO)COCC1=CC=CC=C1)C2=C(C=C(C=C2)F)F
Isomeric SMILES:C=C(C[C@@H](CO)COCC1=CC=CC=C1)C2=C(C=C(C=C2)F)F

Technology Process of Acx53N3fxt

There total 7 articles about Acx53N3fxt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 165115-77-5
(S)-3-[(R)-2-Benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-enoyl]-4-isopropyl-oxazolidin-2-one

: 17016-83-0
(4S)-4-isopropyl-1,3-oxazolidin-2-one

: 165115-78-6
(S)-2-Benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-en-1-ol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃;
DOI:10.1016/0040-4039(96)01203-8

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 165115-78-6
(S)-2-Benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-en-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) TiCl₄; 2.) Et₃N / 1.) CH₂Cl₂, 0 deg C

2: 85 percent / LAH / tetrahydrofuran / 0 °C

With lithium aluminium tetrahydride; titanium tetrachloride; triethylamine; In tetrahydrofuran;
DOI:10.1016/0040-4039(96)01203-8

Reference yield:

: 17690-16-3
benzyl bromomethyl ether

: 165115-78-6
(S)-2-Benzyloxymethyl-4-(2,4-difluoro-phenyl)-pent-4-en-1-ol

Guidance literature:: Multi-step reaction with 2 steps

2: 85 percent / LAH / tetrahydrofuran / 0 °C

With lithium aluminium tetrahydride; In tetrahydrofuran;
DOI:10.1016/0040-4039(96)01203-8