3-Bromo-4-oxo-4-phenyl-N-(3-trifluoromethyl-phenyl)-butyramide

Base Information

• Chemical Name: 3-Bromo-4-oxo-4-phenyl-N-(3-trifluoromethyl-phenyl)-butyramide
• CAS No.: 74457-65-1
• Molecular Formula: C₁₇H₁₃BrF₃NO₂
• Molecular Weight: 400.195
• Mol file: 74457-65-1.mol

Synonyms:3-Bromo-4-oxo-4-phenyl-N-(3-trifluoromethyl-phenyl)-butyramide

Chemical Property of 3-Bromo-4-oxo-4-phenyl-N-(3-trifluoromethyl-phenyl)-butyramide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-Bromo-4-oxo-4-phenyl-N-(3-trifluoromethyl-phenyl)-butyramide

There total 1 articles about 3-Bromo-4-oxo-4-phenyl-N-(3-trifluoromethyl-phenyl)-butyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-bromo-4-oxo-4-phenylbutanoic acid (53515-22-3) + 3-trifluoromethylaniline (98-16-8) → 3-Bromo-4-oxo-4-phenyl-N-(3-trifluoromethyl-phenyl)-butyramide (74457-65-1)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; Yield given;

DOI:10.1016/S0040-4039(00)78822-8

Reference yield: 55.0%

3-Bromo-4-oxo-4-phenyl-N-(3-trifluoromethyl-phenyl)-butyramide (74457-65-1) → 4-Benzoyl-1-(3-trifluoromethyl-phenyl)-azetidin-2-one (74457-67-3)

Guidance literature:

With amberlite IRA-400 anion exchange resin; In ethanol; at 22 ℃; for 0.166667h;

DOI:10.1016/S0040-4039(00)78822-8

upstream raw materials:

3-bromo-4-oxo-4-phenylbutanoic acid

3-trifluoromethylaniline

Downstream raw materials:

4-Benzoyl-1-(3-trifluoromethyl-phenyl)-azetidin-2-one