Technology Process of 1-<2-(1-propoxy-1-phenyl)ethyl>-4-(propananilido)perhydroazepine
There total 8 articles about 1-<2-(1-propoxy-1-phenyl)ethyl>-4-(propananilido)perhydroazepine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: ZnCl2 / toluene / 15 h / Heating
2: NaBH4 / methanol / 1 h / Heating
3: 85 percent / 48percent HBr / 3 h / Heating
4: 92 percent / ethanol / 18 h / Ambient temperature
5: 59 percent / benzene / 10 h / Heating
With
sodium tetrahydroborate; hydrogen bromide; zinc(II) chloride;
In
methanol; ethanol; toluene; benzene;
DOI:10.1002/jhet.5570290417
- Guidance literature:
-
Multi-step reaction with 6 steps
1: K2CO3 / H2O / 4 h / -5 °C
2: ZnCl2 / toluene / 15 h / Heating
3: NaBH4 / methanol / 1 h / Heating
4: 85 percent / 48percent HBr / 3 h / Heating
5: 92 percent / ethanol / 18 h / Ambient temperature
6: 59 percent / benzene / 10 h / Heating
With
sodium tetrahydroborate; hydrogen bromide; potassium carbonate; zinc(II) chloride;
In
methanol; ethanol; water; toluene; benzene;
DOI:10.1002/jhet.5570290417
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 4 N HCl / 6 h / Heating
2: K2CO3 / H2O / 4 h / -5 °C
3: ZnCl2 / toluene / 15 h / Heating
4: NaBH4 / methanol / 1 h / Heating
5: 85 percent / 48percent HBr / 3 h / Heating
6: 92 percent / ethanol / 18 h / Ambient temperature
7: 59 percent / benzene / 10 h / Heating
With
hydrogenchloride; sodium tetrahydroborate; hydrogen bromide; potassium carbonate; zinc(II) chloride;
In
methanol; ethanol; water; toluene; benzene;
DOI:10.1002/jhet.5570290417
