ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate

Base Information

Chemical Name:ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate
CAS No.:1464156-45-3
Molecular Formula:C₂₃H₁₆FN₃O₂
Molecular Weight:385.397
Hs Code.:

Synonyms:ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate

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Technology Process of ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate

There total 5 articles about ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1464156-42-0
ethyl 2-fluoro-4-(3-iodoimidazo[1,2-a]pyridin-6-yl)benzoate

: 126747-14-6
4-cyanophenylboronic acid

: 1464156-45-3
ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate

Guidance literature:: With potassium phosphate; In 1,4-dioxane; water; at 90 ℃; Temperature; Inert atmosphere;

Reference yield: 67.8%

: 874288-38-7
4-(ethoxycarbonyl)-3-fluorophenyl boronic acid

: 1464155-66-5
4-(6-bromoimidazo[1,2-a]pyridin-3-yl)benzonitrile

: 1464156-45-3
ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate

Guidance literature:: With potassium phosphate; In 1,4-dioxane; water; at 100 ℃; Inert atmosphere;

Reference yield:

: 874288-38-7
4-(ethoxycarbonyl)-3-fluorophenyl boronic acid

: 1464156-45-3
ethyl 4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-2-fluorobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium phosphate / water; 1,4-dioxane / 90 °C / Inert atmosphere

2: N-iodo-succinimide / N,N-dimethyl-formamide / 3 h / 100 °C

3: potassium phosphate / water; 1,4-dioxane / 90 °C / Inert atmosphere

With potassium phosphate; N-iodo-succinimide; In 1,4-dioxane; water; N,N-dimethyl-formamide;