methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate

Base Information

Chemical Name:methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate
CAS No.:920511-17-7
Molecular Formula:C₂₆H₃₅N₃O₅
Molecular Weight:469.581
Hs Code.:

Synonyms:methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate

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Chemical Property of methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate

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Technology Process of methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate

There total 1 articles about methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 920511-16-6
methyl 3-(4-formyl-3-methoxyphenyl)-2-pyridinecarboxylate

: 574007-62-8,688363-66-8,180975-66-0,574007-66-2
(2R,6S)-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester

: 920511-17-7
methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate

Guidance literature:: methyl 3-(4-formyl-3-methoxyphenyl)-2-pyridinecarboxylate; (2R,6S)-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester; In 1,2-dichloro-ethane; at 25 ℃;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 25 ℃;

With water; sodium hydrogencarbonate; In 1,2-dichloro-ethane;

Reference yield:

: 920511-17-7
methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate

: 920511-18-8
3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylic acid

Guidance literature:: methyl-3-(4-{[(3R,5S)-3,5-dimethyl-4-tert-butoxycarbonyl-1-piperazinyl]methyl}-3-methoxyphenyl)-2-pyridinecarboxylate; With lithium hydroxide; water; In 1,4-dioxane; at 25 ℃; for 3h;

With hydrogenchloride; In water; pH=5;