4-((2-Oxo-1-oxaspiro(4.5)dec-4-yl)carbonyl)morpholine

Base Information

Chemical Name:4-((2-Oxo-1-oxaspiro(4.5)dec-4-yl)carbonyl)morpholine
CAS No.:136547-41-6
Molecular Formula:C14H21NO4
Molecular Weight:267.3208
Hs Code.:
DSSTox Substance ID:DTXSID70929471
Nikkaji Number:J428.222A
ChEMBL ID:CHEMBL1570726
Mol file:136547-41-6.mol

Synonyms:BRN 5344944;4-((2-Oxo-1-oxaspiro(4.5)dec-4-yl)carbonyl)morpholine;136547-41-6;Morpholine, 4-((2-oxo-1-oxaspiro(4.5)dec-4-yl)carbonyl)-;Oprea1_104338;Oprea1_195476;MLS000532327;CHEMBL1570726;DTXSID70929471;HMS1580G09;HMS2500E11;STL321609;AKOS000505366;AKOS022138878;NCGC00245730-01;LS-93240;SMR000137266;4-Morpholinocarbonyl-1-oxaspiro[4.5]decan-2-one;4-(4-morpholinylcarbonyl)-1-oxaspiro[4.5]decan-2-one;4-(morpholin-4-ylcarbonyl)-1-oxaspiro[4.5]decan-2-one;4-(MORPHOLINE-4-CARBONYL)-1-OXASPIRO[4.5]DECAN-2-ONE

Suppliers and Price of 4-((2-Oxo-1-oxaspiro(4.5)dec-4-yl)carbonyl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-((2-Oxo-1-oxaspiro(4.5)dec-4-yl)carbonyl)morpholine

Chemical Property:

Vapor Pressure:1.66E-10mmHg at 25°C
Boiling Point:509.7°Cat760mmHg
Flash Point:262°C
Density:1.23g/cm³
XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:267.14705815
Heavy Atom Count:19
Complexity:370

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2(CC1)C(CC(=O)O2)C(=O)N3CCOCC3

Technology Process of 4-((2-Oxo-1-oxaspiro(4.5)dec-4-yl)carbonyl)morpholine

There total 2 articles about 4-((2-Oxo-1-oxaspiro(4.5)dec-4-yl)carbonyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 110-91-8,99108-56-2
morpholine

: 30990-88-6
2-oxo-1-oxospiro<4,5>decane-4-carboxyl chloride

: 136547-41-6
4-(Morpholine-4-carbonyl)-1-oxa-spiro[4.5]decan-2-one

Guidance literature:: In benzene; at 60 ℃; for 2h;
DOI:10.1007/BF00772008

Reference yield:

: 2819-56-9
2-oxo-1-oxospiro<4,5>decane-4-carboxylic acid

: 136547-41-6
4-(Morpholine-4-carbonyl)-1-oxa-spiro[4.5]decan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 93.53 percent / thionyl chloride / benzene / 6 h / Heating

2: 73 percent / benzene / 2 h / 60 °C

With thionyl chloride; In benzene;
DOI:10.1007/BF00772008