4-chloromethylphenoxyacetic acid

Base Information

• Chemical Name: 4-chloromethylphenoxyacetic acid
• CAS No.: 77284-29-8
• Molecular Formula: C₉H₉ClO₃
• Molecular Weight: 200.622
• Mol file: 77284-29-8.mol

Synonyms:4-chloromethylphenoxyacetic acid

Chemical Property of 4-chloromethylphenoxyacetic acid

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-chloromethylphenoxyacetic acid

There total 1 articles about 4-chloromethylphenoxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-phenoxyacetic acid (122-59-8) → 4-chloromethylphenoxyacetic acid (77284-29-8)

Guidance literature:

With hydrogenchloride; In water; at -5 ℃; for 0.666667h;

DOI:10.1039/P19810000538

Reference yield: 77.0%

4-chloromethylphenoxyacetic acid (77284-29-8) + 3-hydroxy-3,4-dihydrobenzotriazine-4-one (28230-32-2) → 4-chloromethylphenoxyacetyl-ODhbt (119767-86-1)

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran; at -15 - 20 ℃;

DOI:10.1039/P19880002887

Reference yield: 53.0%

4-chloromethylphenoxyacetic acid (77284-29-8) → [4-(hydroxymethyl)phenoxy]acetic acid (68858-21-9)

Guidance literature:

With sodium hydrogencarbonate; In water;

DOI:10.1039/P19810000538

upstream raw materials:

formaldehyd

2-phenoxyacetic acid

Downstream raw materials:

[4-(hydroxymethyl)phenoxy]acetic acid

4-chloromethylphenoxyacetyl-ODhbt

p-hydroxymethylphenoxyacetic acid 2,4,5-trichlorophenyl ester