Chemical Property of 1-(1-Naphthyl)-2-thiourea
Chemical Property:
- Appearance/Colour:WHITE, ODOURLESS CRYSTALLINE POWDER
- Vapor Pressure:6.69E-06mmHg at 25°C
- Melting Point:193 °C
- Refractive Index:1.5500 (estimate)
- Boiling Point:377.6 °C at 760 mmHg
- PKA:13.12±0.70(Predicted)
- Flash Point:182.1 °C
- PSA：70.14000
- Density:1.333 g/cm3
- LogP:3.26860
- Storage Temp.:Poison room
- Solubility.:4.3 and 86 g/L in acetone and triethylene glycol, respectively (Windholz et al., 1983)
- Water Solubility.:600 mg/L at 20 °C (quoted, Windholz et al., 1983)
- XLogP3:1.7
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:1
- Exact Mass:202.05646950
- Heavy Atom Count:14
- Complexity:217
- Transport DOT Label:Poison
- Purity/Quality:
-
ANTU *data from reagent suppliers
Safty Information:
- Pictogram(s):
TLV: 0.3 mg/m3.
- Hazard Codes:T+
- Statements:
28-40
- Safety Statements:
28-36/37-45-25-23
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Chemical Classes:Pesticides -> Rodenticides
- Canonical SMILES:C1=CC=C2C(=C1)C=CC=C2NC(=S)N
- Inhalation Risk:Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.
- Effects of Short Term Exposure:Exposure could cause lung oedema. Medical observation is indicated.
-
Description
a-Naphthylthiourea (ANTU; also called DIRAX) is toxic by
inhalation, ingestion, or skin contact. Due to its very narrow
spectrum of activity, production was discontinued a long time
ago. Exposure to ANTU causes pulmonary edema; therefore, it
is often used as an experimental pneumotoxin. ANTU is a graycolored,
prism-shaped, odorless powder with a bitter taste. It
has a molecular weight of 202.28 and melting point of 200 ℃
and does not ignite readily. However, on interaction with
potential oxidizing agents, it may cause fire and explosions,
which can lead to hazardous decomposition products such as
sulfur dioxide, nitrogen dioxide, and carbon monoxide. The
structure of ANTU contains the naphthalene chromophore,
which absorbs UV light at ～311 nm. This suggests that ANTU
can undergo photolysis.
-
Physical properties
Colorless crystals when pure. Technical product is grayish-blue. Odorless solid. Bitter taste.
-
Uses
Rodenticide ANTU an organosulfur is a derivative of thiourea. It is a singledose
rodenticide that is specifically used against Norway rats as
a bait. However, it is futile against all other species of rodents.
Because of its tendency to cause resistance and specificity only
toward Norway rodents, this poison rapidly lost popularity and
is no longer manufactured in the United States. Rodenticide. Specific control for the adult Norway rat; less toxic to other rat species.
