(3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol 3-Benzoate

Base Information

Chemical Name:(3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol 3-Benzoate
CAS No.:592536-32-8
Molecular Formula:C₃₁H₄₂O₃
Molecular Weight:462.673
Hs Code.:
Mol file:592536-32-8.mol

Synonyms:(20S)-4,4,20-trimethyl-pregna-5,7-dien-3β,21-diol benzoate

Suppliers and Price of (3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol 3-Benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
(3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol3-Benzoate
10 mg
$ 2600.00

Medical Isotopes, Inc.
(3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol3-Benzoate
1 mg
$ 700.00

Total 1 raw suppliers

Chemical Property of (3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol 3-Benzoate

Chemical Property:

Purity/Quality:: (3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol3-Benzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol 3-Benzoate

There total 8 articles about (3β,20S)-4,4,20-Trimethyl-pregna-5,7-diene-3,21-diol 3-Benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 153005-55-1
tetrabutylammonium fluoride monohydrate

: (20S)-4,4-dimethyl-20-[((triisopropylsilyl)oxy)methyl]-pregna-5,7-dien-3β-ol

: 592536-32-8
(20S)-4,4,20-trimethyl-pregna-5,7-dien-3β,21-diol benzoate

Guidance literature:: molecular sieve; In tetrahydrofuran;

Reference yield:

: 841288-42-4
(20S)-4,4-dimethyl-20-[((triisopropylsilyl)oxy)methyl]-pregna-5,7-dien-3β-ol benzoate

: 592536-32-8
(20S)-4,4,20-trimethyl-pregna-5,7-dien-3β,21-diol benzoate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1021/ol0343156

Reference yield:

: 40736-33-2
(20S)-20-hydroxymethylpregn-4-en-3-one

: 592536-32-8
(20S)-4,4,20-trimethyl-pregna-5,7-dien-3β,21-diol benzoate

Guidance literature:: Multi-step reaction with 7 steps

1: imidazole / CH₂Cl₂ / 4 h / 20 °C

2: t-BuOK / 2-methyl-propan-2-ol / 0.5 h / 20 °C

3: LiAlH₄ / tetrahydrofuran / 0.5 h / 20 °C

4: pyridine / 1 h / 0 °C

5: 1,3-dibromo-5,5-dimethyl-imidazolidine-2,4-dione / benzene; hexane / 0.5 h / 70 °C

6: 2,4,6-trimethylpyridine / toluene / 2 h / Heating

7: tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C

With pyridine; 1H-imidazole; 2,4,6-trimethyl-pyridine; lithium aluminium tetrahydride; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; potassium tert-butylate; tetrabutyl ammonium fluoride; In tetrahydrofuran; hexane; dichloromethane; toluene; tert-butyl alcohol; benzene;
DOI:10.1021/ol0343156