Imidazo[1,2-a]pyridine-3-carbonitrile

Base Information

• Chemical Name: Imidazo[1,2-a]pyridine-3-carbonitrile
• CAS No.: 6200-59-5
• Molecular Formula: C₈H₅N₃
• Molecular Weight: 143.148
• Hs Code.: 2933990090
• Mol file: 6200-59-5.mol

Synonyms:IMIDAZO[1,2-A]PYRIDINE-3-CARBONITRILE;3-cyanoimidazo(1,2-a)pyridine

Chemical Property of Imidazo[1,2-a]pyridine-3-carbonitrile

Chemical Property:

• PSA: 41.09000
• Density: 1.22g/cm³
• LogP: 1.20598
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

imidazo[1,2-a]pyridine-3-carbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Imidazo[1,2-a]pyridine-3-carbonitrile

There total 8 articles about Imidazo[1,2-a]pyridine-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

imidazo[1,2-a]pyridine (274-76-0) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → imidazo[1,2-a]pyridine-3-carbonitrile (6200-59-5)

Guidance literature:

With ammonium iodide; copper(II) nitrate trihydrate; oxygen; acetic acid; at 130 ℃; under 760.051 Torr; Green chemistry;

DOI:10.1039/d0ob01838d

Reference yield: 26.0%

tert-butyl prop-2-yn-1-yl(pyridin-2-yl)carbamate (1284210-49-6) → imidazo[1,2-a]pyridine-3-carbonitrile (6200-59-5) + imidazo[1,2-a]pyridine-3-carbaldehyde (6188-43-8)

Guidance literature:

With copper dichloride; isopentyl nitrite; In acetonitrile; at 65 ℃; for 0.0833333h;

DOI:10.1039/c1cc10641d

Reference yield: 24.0%

N-(prop-2-yn-1-yl)pyridin-2-amine (117459-95-7) → imidazo[1,2-a]pyridine-3-carbonitrile (6200-59-5) + imidazo[1,2-a]pyridine-3-carbaldehyde (6188-43-8)

Guidance literature:

With copper dichloride; isopentyl nitrite; In acetonitrile; at 65 ℃; for 0.5h;

DOI:10.1039/c1cc10641d

upstream raw materials:

tert-butyl prop-2-yn-1-yl(pyridin-2-yl)carbamate

N-(tert-butoxycarbonyl)-2-aminopyridine

N-(prop-2-yn-1-yl)pyridin-2-amine

N,N-dimethyl-N'-pyridin-2-yl-formamidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 6200-59-5 Imidazo[1,2-a]pyridine-3-carbonitrile

Send

Send

Metric Ton KG G Pound L ML

Send

Send