Butaverine

Base Information

Chemical Name:Butaverine
CAS No.:55837-14-4
Molecular Formula:C18H27 N O2
Molecular Weight:289.41
Hs Code.:
UNII:1I5O5WIU8X
DSSTox Substance ID:DTXSID80866505
Nikkaji Number:J11.037J
Wikidata:Q27252451
NCI Thesaurus Code:C73169
ChEMBL ID:CHEMBL2106025

Synonyms:Butaverine;55837-14-4;BUTAMIVERINE;Butaverina;Butaverinum;Butaverine [INN:DCF];UNII-1I5O5WIU8X;1I5O5WIU8X;Butyl 3-phenyl-3-(1-piperidyl)propionate;butyl 3-phenyl-3-piperidin-1-ylpropanoate;butaverine HCl;Butyl 3-phenyl-3-piperidinopropionat;3-Piperidino-3-phenyl-propionsaeure-butylester;BUTAVERINE [MI];BUTAVERINE [INN];1-Piperidinepropanoic acid, .beta.-phenyl-, butyl ester;NCIOpen2_009609;SCHEMBL24501;CHEMBL2106025;BUTAVERINE, (+/-)-;DTXSID80866505;CHEBI:135203;Q27252451

Suppliers and Price of Butaverine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BUTAVERINE 95.00%
5MG
$ 499.35

Total 4 raw suppliers

Chemical Property of Butaverine

Chemical Property:

Vapor Pressure:2.61E-06mmHg at 25°C
Boiling Point:390.6°C at 760 mmHg
Flash Point:125.1°C
PSA：29.54000
Density:1.036g/cm³
LogP:3.88490
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:289.204179104
Heavy Atom Count:21
Complexity:294

Purity/Quality:

99% ^*data from raw suppliers

BUTAVERINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCOC(=O)CC(C1=CC=CC=C1)N2CCCCC2

Technology Process of Butaverine

There total 4 articles about Butaverine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 18991-98-5
n-butyl bromoacetate

: 2538-76-3
1,1'-benzylidenedipiperidine

: 55837-14-4
ethyl 3-phenyl-3-piperidinopropanoate

Guidance literature:: With chloro-trimethyl-silane; diisopropylamine; zinc; In benzene; at 20 ℃; for 6h;
DOI:10.1021/jo8019797

Reference yield:

: 110-89-4
piperidine

: 52392-64-0
(E)-3-(phenyl)acrylic acid butyl ester

: 55837-14-4
ethyl 3-phenyl-3-piperidinopropanoate

Guidance literature:: With tetramethyl ammoniumhydroxide; toluene;
DOI:10.1021/ja01597a062

Reference yield:

: 102-92-1,17082-09-6
Cinnamoyl chloride

: 55837-14-4
ethyl 3-phenyl-3-piperidinopropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; benzene

2: tetramethylammonium hydroxid, aqueous; toluene

With pyridine; tetramethyl ammoniumhydroxide; toluene; benzene;
DOI:10.1021/ja01597a062