2538-76-3

Basic information

• Product Name: Bis(1-piperidinyl)phenylmethane
• Synonyms: 1,1'-Benzylidenedipiperidine;Bis(1-piperidinyl)phenylmethane
• CAS NO: 2538-76-3
• Molecular Formula: C₁₇H₂₆N₂
• Molecular Weight: 258.4017
• Mol File: 2538-76-3.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 340.2°Cat760mmHg
• Flash Point: 145.9°C
• Appearance: /
• Density: 1.047g/cm³
• CAS DataBase Reference: Bis(1-piperidinyl)phenylmethane(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(1-piperidinyl)phenylmethane(2538-76-3)
• EPA Substance Registry System: Bis(1-piperidinyl)phenylmethane(2538-76-3)

Safety Data

• Hazardous Substances Data: 2538-76-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 17, p. 32, 1969 DOI: 10.1248/cpb.17.32

Upstream product

• 110-91-8 morpholine 
• 100-52-7 benzaldehyde 
• 110-89-4 piperidine 
• 121238-80-0 N-<α-(benzotriazol-1-yl)phenylmethyl>piperidine 
• 1865-47-0 piperidine sodium 
• 122699-86-9 1-(Bromo-phenyl-methyl)-pyridinium; bromide 
• 4222-25-7 3-bromo-3-phenyl-3H-diazirine 
• 92-29-5 hydrobenzamide 
• 3768-56-7 1-(trimethylsilyl)piperidine 
• 811-98-3 d⁽⁴⁾-methanol 

Downstream Products

• 38608-50-3 3-(phenyl(piperidin-1-yl)methyl)pyridine 
• 35278-83-2 1-(1-phenylbut-3-en-1-yl)piperidine 
• 1082512-40-0 2-methyl-4-phenyl-4-piperidino-1-butene 
• 94533-57-0 meso-N,N,N',N'-bis(pentamethylen)-1,2-diphenylaethylendiamin 
• 94533-64-9 (+/-)-N,N,N',N'-bis(pentamethylen)-1,2-diphenylaethylendiamin 
• 1082512-39-7 3,3-dimethyl-4-phenyl-4-piperidino-1-butene 
• 120173-16-2 ethyl 3-phenyl-3-piperidinopropanoate 
• 36794-52-2 (±)-1-(1,2-diphenylethyl)piperidine 
• 55837-14-4 ethyl 3-phenyl-3-piperidinopropanoate 
• 1165-06-6 Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 119569-83-4 3,13-dibenzylidene-cyclotridecane-1,2-dione 
• 102952-61-4 3,11-dibenzylidene-cycloundecane-1,2-dione 
• 10527-66-9 1-benzhydryl-piperidine 
• 102714-44-3 (2E)-1,3-diphenyl-2-phenylsulfinyl-2-propen-1-one 

Relevant articles and documents

S,S-Complexes of Copper(I) Halides with 1,2-Bis(3,5-dimethyloxazol-4-ylmethylsulfanyl)ethane as New Catalysts for Phenylacetylene Aminomethylation

New metal–heterocycle S,S-complexes based on Cu(I) binary halides and a polydentate ligand, 1,2- bis(3,5-dimethyloxazol-4-ylmethylsulfanyl)ethane have been prepared. The obtained complexes have demonstrated high catalytic activity in aminomethylation of p

Atom-efficient transition-metal-free arylation ofN,O-acetals using diarylzinc reagents through Zn/Zn cooperativity

Exploiting the cooperative action of Lewis acid Zn(C6F5)2with diarylzinc reagents, the efficient arylation ofN,O-acetals to access diarylmethylamines is reported. Reactions take place under mild reaction conditions without the need for transtion-metal catalysis. Mechanistic investigations have revealed that Zn(C6F5)2not only acts as a Lewis acid activator, but also enables the regeneration of nucleophilic ZnAr2species, allowing a limiting 50 mol% to be employed.

Zinc-mediated allylation and alkylation of aminals in the presence of TMSCl and diisopropylamine

(Chemical Equation Presented) An alkylation of aminals with organozinc reagents derived from allyl bromide, benzyl bromide, α-bromoacetate, and α-bromonitrile proceeded efficiently in the presence of TMSCl and diisopropylamine. This reaction system was applied to the synthesis of an antispasmodic: butaverine.