5,11,17,23-tetrakis<(p-carboxyphenyl)azo>-25,26,27,28-tetrahydroxycalix<4>arene

Base Information

• Chemical Name: 5,11,17,23-tetrakis<(p-carboxyphenyl)azo>-25,26,27,28-tetrahydroxycalix<4>arene
• CAS No.: 125583-12-2
• Molecular Formula: C₅₆H₄₀N₈O₁₂
• Molecular Weight: 1016.98
• Mol file: 125583-12-2.mol

Synonyms:5,11,17,23-tetrakis<(p-carboxyphenyl)azo>-25,26,27,28-tetrahydroxycalix<4>arene

Chemical Property of 5,11,17,23-tetrakis<(p-carboxyphenyl)azo>-25,26,27,28-tetrahydroxycalix<4>arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,11,17,23-tetrakis<(p-carboxyphenyl)azo>-25,26,27,28-tetrahydroxycalix<4>arene

There total 7 articles about 5,11,17,23-tetrakis<(p-carboxyphenyl)azo>-25,26,27,28-tetrahydroxycalix<4>arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

25,26,27,28-tetrakis(hydroxy)calix[4]arene (248590-47-8,74568-07-3) + 4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → 5,11,17,23-tetrakis[(p-carboxyphenyl)azo]-25,26,27,28-tetra-hydroxy calix[4]arene (125583-12-2)

Guidance literature:

With hydrogenchloride; sodium acetate; sodium nitrite; In methanol; water; N,N-dimethyl-formamide; at 2 - 20 ℃; for 2h;

DOI:10.1002/anie.201813397

Reference yield: 81.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-(4-hydroxyphenylazo)benzoic acid (105299-45-4) → 5,11,17,23-tetrakis<(p-carboxyphenyl)azo>-25,26,27,28-tetrahydroxycalix<4>arene (125583-12-2)

Guidance literature:

formaldehyd; 4-(4-hydroxyphenylazo)benzoic acid; With sodium hydroxide; In diphenylether; for 3h; Reflux;

With sodium tetraborate decahydrate; In ethylene glycol; for 2h; Reflux;

Reference yield:

para-tert-butylphenol (98-54-4) → 5,11,17,23-tetrakis[(p-carboxyphenyl)azo]-25,26,27,28-tetra-hydroxy calix[4]arene (125583-12-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydroxide / water / 0.08 h / Microwave irradiation

1.2: 0.25 h / Microwave irradiation

2.1: aluminum (III) chloride; phenol / toluene

3.1: hydrogenchloride; sodium nitrite / 0 - 5 °C

With hydrogenchloride; aluminum (III) chloride; sodium hydroxide; sodium nitrite; phenol; In water; toluene;

DOI:10.1007/s10847-009-9669-8

upstream raw materials:

25,26,27,28-tetrakis(hydroxy)calix[4]arene

4-carboxybenzenediazonium chloride

4-amino-benzoic acid

formaldehyd

Downstream raw materials:

C₆₀H₅₂N₄O₁₂