Technology Process of C20H17F3N2O3
There total 7 articles about C20H17F3N2O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: palladium diacetate; sodium carbonate / 1,2-dimethoxyethane; water / 3 h / Inert atmosphere; Reflux
2: sodium tetrahydroborate; ethanol / 1 h / 20 °C / Cooling with ice
3: phosphorus tribromide / diethyl ether / 1.5 h / 20 °C / Cooling with ice
4: copper(l) iodide; tetra-(n-butyl)ammonium iodide; potassium carbonate / acetonitrile / 4 h / 40 °C / Inert atmosphere
5: triethylamine / N,N-dimethyl-formamide / 3 h / 70 °C / Inert atmosphere
6: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
With
sodium tetrahydroborate; copper(l) iodide; ethanol; palladium diacetate; phosphorus tribromide; tetra-(n-butyl)ammonium iodide; sodium carbonate; potassium carbonate; triethylamine; trifluoroacetic acid;
In
1,2-dimethoxyethane; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium tetrahydroborate; ethanol / 1 h / 20 °C / Cooling with ice
2: phosphorus tribromide / diethyl ether / 1.5 h / 20 °C / Cooling with ice
3: copper(l) iodide; tetra-(n-butyl)ammonium iodide; potassium carbonate / acetonitrile / 4 h / 40 °C / Inert atmosphere
4: triethylamine / N,N-dimethyl-formamide / 3 h / 70 °C / Inert atmosphere
5: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
With
sodium tetrahydroborate; copper(l) iodide; ethanol; phosphorus tribromide; tetra-(n-butyl)ammonium iodide; potassium carbonate; triethylamine; trifluoroacetic acid;
In
diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetonitrile;