(3-Amino-7-methoxybenzofuran-2-yl)(phenyl)methanone

Base Information

Chemical Name:(3-Amino-7-methoxybenzofuran-2-yl)(phenyl)methanone
CAS No.:269075-50-5
Molecular Formula:C₁₆H₁₃NO₃
Molecular Weight:267.284
Hs Code.:
European Community (EC) Number:668-998-6

Synonyms:(3-Amino-7-methoxybenzofuran-2-yl)(phenyl)methanone;269075-50-5;AKOS022183804;2-BENZOYL-7-METHOXY-1-BENZOFURAN-3-AMINE;(3-amino-7-methoxy-1-benzofuran-2-yl)(phenyl)methanone

Suppliers and Price of (3-Amino-7-methoxybenzofuran-2-yl)(phenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of (3-Amino-7-methoxybenzofuran-2-yl)(phenyl)methanone

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:267.08954328
Heavy Atom Count:20
Complexity:354

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC2=C1OC(=C2N)C(=O)C3=CC=CC=C3

Technology Process of (3-Amino-7-methoxybenzofuran-2-yl)(phenyl)methanone

There total 3 articles about (3-Amino-7-methoxybenzofuran-2-yl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 269075-65-2
3-Methoxy-2-(2-oxo-2-phenylethoxy)benzonitrile

: 269075-50-5
2-Benzoyl-7-methoxy-1-benzofuran-3-amine

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 0.5h;
DOI:10.1135/cccc20000280

Reference yield:

: 6812-16-4
2-Hydroxy-3-methoxybenzonitrile

: 269075-50-5
2-Benzoyl-7-methoxy-1-benzofuran-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / K₂CO₃ / dimethylformamide / 2 h / 20 °C

2: 75 percent / NaOMe / methanol / 0.5 h / 20 °C

With sodium methylate; potassium carbonate; In methanol; N,N-dimethyl-formamide; 1: Etherification / 2: Cyclization;
DOI:10.1135/cccc20000280

Reference yield:

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 269075-50-5
2-Benzoyl-7-methoxy-1-benzofuran-3-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / NH₂OH*HCl; NaOAc; HCOOH / 3 h / Heating

2: 67 percent / K₂CO₃ / dimethylformamide / 2 h / 20 °C

3: 75 percent / NaOMe / methanol / 0.5 h / 20 °C

With formic acid; hydroxylamine hydrochloride; sodium methylate; sodium acetate; potassium carbonate; In methanol; N,N-dimethyl-formamide; 1: Condensation / 2: Etherification / 3: Cyclization;
DOI:10.1135/cccc20000280