(4-Bromo-benzylidene)-(2-(3,4-dimethoxy-phenyl)-ethyl)-amine

Base Information

Chemical Name:(4-Bromo-benzylidene)-(2-(3,4-dimethoxy-phenyl)-ethyl)-amine
CAS No.:96315-77-4
Molecular Formula:C₁₇H₁₈BrNO₂
Molecular Weight:348.239
Hs Code.:
European Community (EC) Number:684-982-1

Synonyms:(4-BROMO-BENZYLIDENE)-(2-(3,4-DIMETHOXY-PHENYL)-ETHYL)-AMINE;AKOS024330729

Suppliers and Price of (4-Bromo-benzylidene)-(2-(3,4-dimethoxy-phenyl)-ethyl)-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-Bromo-benzylidene)-(2-(3,4-dimethoxy-phenyl)-ethyl)-amine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:347.05209
Heavy Atom Count:21
Complexity:316

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CCN=CC2=CC=C(C=C2)Br)OC

Technology Process of (4-Bromo-benzylidene)-(2-(3,4-dimethoxy-phenyl)-ethyl)-amine

There total 1 articles about (4-Bromo-benzylidene)-(2-(3,4-dimethoxy-phenyl)-ethyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 1122-91-4
4-bromo-benzaldehyde

: 96315-77-4
C₁₇H₁₈BrNO₂

Guidance literature:: at 90 ℃; for 0.0833333h; under 10343.2 Torr; Microwave irradiation;
DOI:10.1016/j.bmc.2009.03.066

Reference yield:

: 96315-77-4
C₁₇H₁₈BrNO₂

: 96315-84-3
1-(4-bromo-phenyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline

Guidance literature:: C₁₇H₁₈BrNO₂; With trifluoroacetic acid; at 90 ℃; for 0.0833333h; under 10343.2 Torr; Microwave irradiation;

With sodium hydroxide; In water;
DOI:10.1016/j.bmc.2009.03.066

Reference yield:

: 96315-77-4
C₁₇H₁₈BrNO₂

: 4-[1-(4-bromophenyl)-6,7-dihydroxy-3,4-dihydro-1H-isoquinoline-2-carbonyl]benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: trifluoroacetic acid / 0.17 h / Microwave irradiation; Heating

2.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / 1 h / 20 °C

2.2: 20 °C

3.1: dichloromethane / 20 °C / Inert atmosphere

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.7b00264