Technology Process of 17-chloro-5α-cholestane-3β,5-diol 3-acetate 5-(4-iodophenyl)acetate
There total 6 articles about 17-chloro-5α-cholestane-3β,5-diol 3-acetate 5-(4-iodophenyl)acetate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sulfuryl dichloride; 2,2'-azobis(isobutyronitrile);
In
tetrachloromethane;
at -10 ℃;
for 2.5h;
Irradiation;
DOI:10.1016/S0040-4020(01)82345-0
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) O2, 2.) H2 / 2.) PtO2*H2O / 1.) CH2Cl2/pyridine, irradiation, 14 h, 15 deg C, 2.) ethyl acetate, room temperature, atmospheric pressure, 10 h
2: 74 percent / calcium hydride, tetra-n-butylammonium iodide / toluene / Heating
3: 59 percent / azobis(isobutyronitrile), SO2Cl2 / CCl4 / 2.5 h / -10 °C / Irradiation
With
sulfuryl dichloride; calcium hydride; 2,2'-azobis(isobutyronitrile); hydrogen; oxygen; tetra-(n-butyl)ammonium iodide;
platinum(IV) oxide;
In
tetrachloromethane; toluene;
DOI:10.1016/S0040-4020(01)82345-0
- Guidance literature:
-
Multi-step reaction with 4 steps
1: pyridine
2: 1.) O2, 2.) H2 / 2.) PtO2*H2O / 1.) CH2Cl2/pyridine, irradiation, 14 h, 15 deg C, 2.) ethyl acetate, room temperature, atmospheric pressure, 10 h
3: 74 percent / calcium hydride, tetra-n-butylammonium iodide / toluene / Heating
4: 59 percent / azobis(isobutyronitrile), SO2Cl2 / CCl4 / 2.5 h / -10 °C / Irradiation
With
pyridine; sulfuryl dichloride; calcium hydride; 2,2'-azobis(isobutyronitrile); hydrogen; oxygen; tetra-(n-butyl)ammonium iodide;
platinum(IV) oxide;
In
tetrachloromethane; toluene;
DOI:10.1016/S0040-4020(01)82345-0
