phendimetrazine

Base Information

• Chemical Name: phendimetrazine
• CAS No.: 21784-30-5
• Molecular Formula: C12H17 N O
• Molecular Weight: 191.273
• Hs Code.: 2934999090
• Mol file: 21784-30-5.mol

Synonyms:17140-98-6 (Hydrochloride);Bontril;Dyrexan;Hyrex;Wehless;X-Trozine

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of phendimetrazine

Chemical Property:

• Vapor Pressure: 0.00514mmHg at 25°C
• Boiling Point: 275.3°Cat760mmHg
• Flash Point: 80.9°C
• PSA: 12.47000
• Density: 0.992g/cm³
• LogP: 2.01610

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of phendimetrazine

There total 9 articles about phendimetrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + trans-Phenmetrazine (134-49-6,1618-50-4,13580-23-9,57919-12-7,63971-50-6,84025-82-1,21288-73-3) → trans-Phendimetrazine (634-03-7,711-72-8,21784-30-5,27032-15-1,29493-75-2,38323-36-3)

Guidance literature:

With formic acid; In water; at 25 ℃; Reflux;

DOI:10.1021/ja104168q

Reference yield:

(2-hydroxyethyl)(methyl)amine (109-83-1) + acetic acid 1-methyl-2-oxo-2-phenyl-ethyl ester (19347-08-1) → trans-Phendimetrazine (634-03-7,711-72-8,21784-30-5,27032-15-1,29493-75-2,38323-36-3) + 3,4-dimethyl-2-phenyl-morpholine (634-03-7,711-72-8,21784-30-5,27032-15-1,29493-75-2,38323-36-3)

Guidance literature:

With formic acid; at 180 ℃; for 20h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1002/ardp.19903230111

Reference yield:

(2-hydroxyethyl)(methyl)amine (109-83-1) + acetic acid 1-methyl-2-oxo-2-phenyl-ethyl ester (19347-08-1) → trans-Phendimetrazine (634-03-7,711-72-8,21784-30-5,27032-15-1,29493-75-2,38323-36-3) + 3,4-dimethyl-2-phenyl-morpholine (634-03-7,711-72-8,21784-30-5,27032-15-1,29493-75-2,38323-36-3)

Guidance literature:

With formic acid; at 180 ℃; for 20h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1002/ardp.19903230111

upstream raw materials:

(1RS,2SR)-2-[(2-hydroxy-ethyl)-methyl-amino]-1-phenyl-propan-1-ol

(2-hydroxyethyl)(methyl)amine

acetic acid 1-methyl-2-oxo-2-phenyl-ethyl ester

2-bromo-1-phenyl-1-propanone

Downstream raw materials:

phendimetrazine N-oxide

3-Methyl-2-phenyl-morpholine-4-carboxylic acid ethyl ester

phenmetrazine hydrochloride

trans-Phenmetrazine