2,4-Dimethylpiperidine

Base Information

• Chemical Name: 2,4-Dimethylpiperidine
• CAS No.: 6287-19-0
• Molecular Formula: C₇H₁₅N
• Molecular Weight: 113.203
• Hs Code.: 2933399090
• NSC Number: 8693
• DSSTox Substance ID: DTXSID50978604
• Mol file: 6287-19-0.mol

Synonyms:2,4-Dimethylpiperidine;6287-19-0;Piperidine, 2,4-dimethyl-;2,4-dimethyl-piperidine;2,4-dimethylpiperidin;dl-2,4-dimethyl-piperidine;NSC8693;2,4-lupetidine;NSC 8693;2,4-Dimethyl piperidine;UNII-8H9YP8Q5ZN;8H9YP8Q5ZN;SCHEMBL24367;DTXSID50978604;2,4-dimethylpiperidine(HCl form);NSC-8693;BBL038129;MFCD00129009;STL573307;AKOS000305903;AC-16581;FT-0610186;EN300-61909;D87679;A834054

Chemical Property of 2,4-Dimethylpiperidine

Chemical Property:

• Vapor Pressure: 5.93mmHg at 25°C
• Refractive Index: 1.416
• Boiling Point: 141.2 °C at 760 mmHg
• Flash Point: 28.6 °C
• PSA: 12.03000
• Density: 0.794 g/cm³
• LogP: 1.72320
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 113.120449483
• Heavy Atom Count: 8
• Complexity: 70.8

Purity/Quality:

97% ^*data from raw suppliers

2,4-Dimethylpiperidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCNC(C1)C

Technology Process of 2,4-Dimethylpiperidine

There total 10 articles about 2,4-Dimethylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-lutidine (108-47-4) → trans-2,4-dimethylpiperidine (6287-19-0,19683-91-1,19683-92-2) + cis-2,4-dimethylpiperidine (6287-19-0,19683-91-1,19683-92-2)

Guidance literature:

With hydrogenchloride; hydrogen; sodium; platinum(IV) oxide; Yield given. Multistep reaction. Yields of byproduct given; 1) EtOH, reflux; 2) 9 percent HCl;

DOI:10.1021/ja00316a001

Reference yield:

2,4-lutidine (108-47-4) → trans-2,4-dimethylpiperidine (6287-19-0,19683-91-1,19683-92-2) + cis-2,4-dimethylpiperidine (6287-19-0,19683-91-1,19683-92-2)

Guidance literature:

With hydrogenchloride; hydrogen; sodium; platinum(IV) oxide; Yield given. Multistep reaction. Yields of byproduct given; 1) EtOH, reflux; 2) 9 percent HCl;

DOI:10.1021/ja00316a001

Reference yield:

2,4-lutidine (108-47-4) → dl-2,4-dimethyl-piperidine (6287-19-0)

Guidance literature:

With nickel; Hydrogenation;

DOI:10.1021/ja01216a051

upstream raw materials:

2,4-lutidine

ethanol

pentan-1-ol

3-methyl-5-oxo-hexanenitrile

Downstream raw materials:

1-{3-[4-(1,1-dimethylethyl)phenyl]-2-methyl-2-propenyl}-2,4-dimethyl-piperidine