Technology Process of 2-({2-[(4-butylphenyl)amino]-9H-purin-9-yl}methoxy)ethanol
There total 5 articles about 2-({2-[(4-butylphenyl)amino]-9H-purin-9-yl}methoxy)ethanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; potassium carbonate;
palladium on activated charcoal;
In
ethanol;
for 12h;
under 2585.7 Torr;
DOI:10.1021/jm00384a019
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 96 percent / phosphoryl chloride, N,N-dimethylaniline / 0.17 h / Heating
2: 1.) NaH / 1.) MeCN, RT, 30 min, 2.) MeCN, RT, 20 min
3: 81 percent / K2CO3, H2 / 10percent Pd/C / aq. ethanol / 12 h / 2585.7 Torr
With
hydrogen; sodium hydride; potassium carbonate; N,N-dimethyl-aniline; trichlorophosphate;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jm00384a019
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 4-butylaniline hydrochloride / 2-methoxy-ethanol / Heating
2: 96 percent / phosphoryl chloride, N,N-dimethylaniline / 0.17 h / Heating
3: 1.) NaH / 1.) MeCN, RT, 30 min, 2.) MeCN, RT, 20 min
4: 81 percent / K2CO3, H2 / 10percent Pd/C / aq. ethanol / 12 h / 2585.7 Torr
With
hydrogen; sodium hydride; potassium carbonate; p-butylaniline hydrochloride; N,N-dimethyl-aniline; trichlorophosphate;
palladium on activated charcoal;
In
ethanol; 2-methoxy-ethanol;
DOI:10.1021/jm00384a019
