1-(3,5-dimethoxyphenyl)-2-hydroxytridecane

Base Information

• Chemical Name: 1-(3,5-dimethoxyphenyl)-2-hydroxytridecane
• CAS No.: 168697-62-9
• Molecular Formula: C₂₁H₃₆O₃
• Molecular Weight: 336.515
• Mol file: 168697-62-9.mol

Synonyms:1-(3,5-dimethoxyphenyl)-2-hydroxytridecane

Chemical Property of 1-(3,5-dimethoxyphenyl)-2-hydroxytridecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3,5-dimethoxyphenyl)-2-hydroxytridecane

There total 6 articles about 1-(3,5-dimethoxyphenyl)-2-hydroxytridecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Dodecanal (112-54-9) + 3,5-dimethoxybenzylchloride (6652-32-0) → 1-(3,5-dimethoxyphenyl)-2-hydroxytridecane (168697-62-9)

Guidance literature:

3,5-dimethoxybenzylchloride; With manganese; In tetrahydrofuran; at 20 ℃; for 0.333333h;

Dodecanal; In tetrahydrofuran; at 20 ℃; for 1h; Further stages.;

DOI:10.1021/jo991478s

Reference yield: 71.0%

1-(3,5-dimethoxyphenyl)tridecan-2-one (155184-20-6) → 1-(3,5-dimethoxyphenyl)-2-hydroxytridecane (168697-62-9)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 3h; Heating;

Reference yield: 37.0%

Dodecanal (112-54-9) + 3,5-dimethoxybenzyl trimethylsilyl ether (185249-83-6) → 1-(3,5-dimethoxyphenyl)-2-hydroxytridecane (168697-62-9)

Guidance literature:

With naphthalene; lithium; In tetrahydrofuran; at 0 ℃; for 2h;

DOI:10.1021/jo9610624

upstream raw materials:

1-(3,5-dimethoxyphenyl)tridecan-2-one

Dodecanal

3,5-dimethoxybenzyl trimethylsilyl ether

3,5-dimethoxybenzylchloride

Downstream raw materials:

(+/-)-1-(2-carboxy-3,5-dimethoxyphenyl)tridecan-2-yl acetate

(+/-)-1-(2-formyl-3,5-dimethoxyphenyl)tridecan-2-yl acetate

Methanesulfonic acid 1-(3,5-dimethoxy-benzyl)-dodecyl ester

5-tridecylresorcinol

Refernces

• 1、 Kim, Seung-Hoi,Rieke, Reuben D.. "Benzylic Manganese Halides, Sulfonates, and Phosphates: Preparation, Coupling Reactions, and Applications in Organic Synthesis". . p. 2322 - 2330. Retrieved 2007/10/03.
• 2、 Rama, Nasim H.,Saeed, Aamer,Bird, Clive W.. "The Synthesis of the Principal Dihydroisocoumarins of Ononis natrix". . p. 1331 - 1334. Retrieved 2007/10/02.