2'-Hydroxy-5'-methyl-2-nitrochalcon

Base Information

• Chemical Name: 2'-Hydroxy-5'-methyl-2-nitrochalcon
• CAS No.: 52790-82-6
• Molecular Formula: C₁₆H₁₃NO₄
• Molecular Weight: 283.284
• Mol file: 52790-82-6.mol

Synonyms:2'-Hydroxy-5'-methyl-2-nitrochalcon

Chemical Property of 2'-Hydroxy-5'-methyl-2-nitrochalcon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2'-Hydroxy-5'-methyl-2-nitrochalcon

There total 3 articles about 2'-Hydroxy-5'-methyl-2-nitrochalcon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-5-methylphenylethanone + 2-nitro-benzaldehyde (552-89-6) → 2'-Hydroxy-5'-methyl-2-nitrochalcon (52790-82-6)

Guidance literature:

With sodium hydroxide; In methanol; water; at 25 ℃; for 20h;

DOI:10.1016/j.molstruc.2021.130052

Reference yield:

5-methyl-2-hydroxyacetophenone (1450-72-2) + 2-nitro-benzaldehyde (552-89-6) → 1-(2-hydroxy-5-methyl-phenyl)-3-(2-nitro-phenyl)-propenone (52790-82-6)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.jfluchem.2012.03.006

Reference yield:

→ 1-(2-hydroxy-5-methyl-phenyl)-3-(2-nitro-phenyl)-propenone (52790-82-6)

Guidance literature:

2-Nitrozimtsaeurechlorid, 4-Methoxytoluol;

DOI:10.1039/P19740000583

upstream raw materials:

2-nitro-benzaldehyde

5-methyl-2-hydroxyacetophenone

Downstream raw materials:

2-[2]quinolyl-4-methyl-phenol