tert-butyl 1-(4-chloro-3-fluorobenzyl)-4-piperidinylcarbamate

Base Information

• Chemical Name: tert-butyl 1-(4-chloro-3-fluorobenzyl)-4-piperidinylcarbamate
• CAS No.: 328084-00-0
• Molecular Formula: C₁₇H₂₄ClFN₂O₂
• Molecular Weight: 342.841
• Mol file: 328084-00-0.mol

Synonyms:tert-butyl 1-(4-chloro-3-fluorobenzyl)-4-piperidinylcarbamate

Chemical Property of tert-butyl 1-(4-chloro-3-fluorobenzyl)-4-piperidinylcarbamate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of tert-butyl 1-(4-chloro-3-fluorobenzyl)-4-piperidinylcarbamate

There total 1 articles about tert-butyl 1-(4-chloro-3-fluorobenzyl)-4-piperidinylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(piperidin-4-yl)carbamic acid tert-butyl ester (73874-95-0) + 4-chloro-3-fluorobenzaldehyde (5527-95-7) → tert-butyl 1-(4-chloro-3-fluorobenzyl)-4-piperidinylcarbamate (328084-00-0)

Guidance literature:

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; for 24h;

Reference yield:

tert-butyl 1-(4-chloro-3-fluorobenzyl)-4-piperidinylcarbamate (328084-00-0) → 1-(4-chloro-3-fluorobenzyl)-4-piperidinamine

Guidance literature:

With trifluoroacetic acid; In dichloromethane; for 2h;

upstream raw materials:

(piperidin-4-yl)carbamic acid tert-butyl ester

4-chloro-3-fluorobenzaldehyde