(R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one

Base Information

Chemical Name:(R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one
CAS No.:1191954-37-6
Molecular Formula:C₂₅H₃₁NO₃Si
Molecular Weight:421.612
Hs Code.:

Synonyms:(R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one

Suppliers and Price of (R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of (R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one

There total 4 articles about (R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₅H₃₃NO₄Si

: 1191954-37-6
(R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one

Guidance literature:: C₂₅H₃₃NO₄Si; With trimethylsilyl trifluoromethanesulfonate; triethylamine; In dichloromethane; for 72h; Reflux; Inert atmosphere;

With acetic acid; at 20 ℃; for 0.5h;
DOI:10.1002/adsc.200800789

Reference yield:

: 119619-48-6
(R)-<(tert-butyldimethylsilyl)oxy>phenylacetic acid

: 1191954-37-6
(R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; hexane / -40 °C / Inert atmosphere

1.2: Inert atmosphere; Cooling

1.3: 20 °C / Inert atmosphere; Cooling

2.1: trimethylsilyl trifluoromethanesulfonate; triethylamine / dichloromethane / Inert atmosphere; Reflux

With n-butyllithium; trimethylsilyl trifluoromethanesulfonate; triethylamine; In diethyl ether; hexane; dichloromethane;
DOI:10.3762/bjoc.7.108

Reference yield:

: C₂₅H₃₃NO₄Si

: 1191954-37-6
(R)-6-[(tert-butyldimethylsiloxy)phenylmethyl]-3-methoxy-2-phenylpyridin-4(1H)-one

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; triethylamine; In dichloromethane; Inert atmosphere; Reflux;
DOI:10.3762/bjoc.7.108